Until 1917, the area around Kanatchikovo Station was not part of the city and consisted of lands with sparse construction of villages and hamlets. This region was considered county land and was managed by the Moscow county zemstvo, effectively being the outskirts of Moscow. To the northeast of the station were the lands of Princess Obolenskaya, to the east, urban lands (since 1907), and to the south, across the Semyonovsky stream, lay the Kanatchikovo dacha, the name of which was also given to the station.

Kanatchikovo Station was used for passenger and freight traffic, as well as for exchanging cars with the Ryazan-Ural Railway (now the Pavelskoye direction of the Moscow Railway) through connecting branches No. 20 (Kanatchikovo, Kolomenskoe) and 21 (Kanatchikovo, Moscow-freight, Pavelskaya).

Branch No. 20 was particularly important, as it was used for delivering coal from the "Donbass Super-Mainline" (as the Pavelskoye direction was called in the 1930s) to the Moscow CHPP-20, which was put into operation in 1952. Branch No. 20 was long, with ascents and descents, and to facilitate train traction, it was electrified with alternating current in the early 1960s. This was the only case of using alternating current for train traction in the Moscow hub. In the 1980s, after CHPP-20 switched to gas, electric locomotives were no longer used, and the overhead line was dismantled, leaving only a few supports.

The station building of Kanatchikovo is a two-story structure with arched windows, cornices, and two lion head images on either side of the entrance. The facade features the station's name in the "signature" font of the Moscow Circular Railway in the "modern" style. Above the entrance, a historical plaque remains indicating the station's height above sea level, 66.3 fathoms, which corresponds to 132.6 meters in the modern measurement system. This is the level of the Baltic Sea, from which the level of all stations of the Nikolaev Railway, including the Circular Railway, was measured. Inside the station, there were three large halls: first, second, and third class, which differed significantly from each other. In first class, there was a large iconostasis in the corner, and the soft sofas were covered with white canvas covers. In second class, there were also sofas, but they were hard and wooden. The third-class hall had no furniture, and visitors could sit on the floor.

In addition to the station, there is a residential building with apartments for the station's management, a brick fire shed, a warehouse, and a toilet with a lamp. Eight lanterns from 1908 have been preserved in front of the station.

This platform was the meeting place of the characters Giovanna and Antonio from the film "Sunflower" (USSR, Italy, directed by Vittorio De Sica, 1969), played by Sophia Loren and Marcello Mastroianni. Scenes from the film "The Cranes Are Flying" (directed by M.K. Kalatozov, 1957) were also filmed in Kanatchikovo, and several scenes from A.A. Tarkovsky's film "Stalker" (1979) were shot on the tracks of CHPP-20.