Archival data about the Church of St. Nicholas the Wonderworker in the village of Multanova is scarce, as it was built shortly before the revolution. In a small fishing settlement that arose on the river Maly Lebyazhiy in the lower Volga, there was no parish church, but there was a wooden chapel in honor of St. Nicholas the Wonderworker. By 1908, Multanova had about 100 households with a population of 580 people. The residents were Russians, immigrants from the upper provinces of Russia, and adhered to Orthodoxy. Old Believers also came here but found no support. The settlement was located a few versts from the well-known male monastery in the Astrakhan province, the Vysogorsk Nikolo-Churkinskaya Desert. Officially, it was attached to the parish of the Kazan Church in the village of Marfino, where two priests served at the beginning of the 20th century. On major holidays and during Great Lent, one of them would come to Multanova to administer communion and serve prayers in the chapel. By 1907, the old chapel had deteriorated and could not accommodate all the parishioners. The residents decided to build a new, more spacious chapel, but ultimately constructed a small church, consecrated in 1909. The "Astrakhan Diocesan Gazette" for 1909 mentions an article about the consecration of the church in Multanova, signed with the initials "V.P." It is likely that the author was the rector of the Marfino church, Vladimir Polyakov, under whose guidance the church was built.

The Church of St. Nicholas in Multanova remained attached to the parish of the Kazan Church in the village of Marfino. The residents wanted to have their own priest, but due to the small population and lack of funds, this was not possible. The construction of the church continued even after 1909, culminating in the addition of a refectory and a two-tiered bell tower with an octagonal tent.

On September 18, 1917, by the order of Archbishop Mitrofan Krasnopolsky of Astrakhan and Yenotayevsk, an independent parish was opened in Multanova, and the priest became Vasily Khatuntsov, a graduate of the Astrakhan Theological Seminary.

In 1922, during the confiscation of church valuables, silver liturgical utensils were confiscated from the Multanova church on August 22. The total weight of the confiscated silver amounted to 6 pounds 77.5 zolotniks.

The community of believers continued to use the church until 1940, when most churches had already been closed. The protocol of the Volodarsky district executive committee dated September 18, 1940, noted that the community was using the church and its property illegally, as there was no agreement for use.

The church in Multanova was closed on October 25, 1940, by the decision of the executive committee of the Astrakhan regional council. On September 24, 1941, it was decided to transfer the buildings of closed churches, including the church in Multanova, to the state fund for dismantling and sale as construction material. However, likely due to the onset of war, the church survived and was used as a storage facility. Currently, it is undergoing gradual restoration.