The village was founded during the reign of Ivan IV the Terrible at the site of the miraculous appearance of the icon of Saint Nicholas the Wonderworker. This event occurred around 1550. According to legend, a merchant caravan of the Stroganov boyars, sailing down the Kama River, was miraculously halted on the river and could only continue its journey after the icon of Saint Nicholas was found on the shore. Later, the icon was taken to Moscow by Tsar Ivan, who adorned it with a silver-gold robe. During the Bashkir uprisings and Pugachev's rebellion, the icon was hidden and even buried in the ground.

The first church in honor of Saint Nicholas was built by P.S. Stroganov soon after the discovery of the icon. Very little information has survived about the second church; it is known only that it was also dedicated to Nicholas and burned down around 1613. The third church, the Trinity Church with a Nicholas chapel, was marked by an iron monument at the site of the icon's appearance, which existed until 1934. In 1774, the Pugachevites burned down another church.

The modern brick church, built between 1806 and 1816, is considered the fourth or fifth in the village. Its main part, executed in the style of late Baroque with elements of Classicism, was completed in 1808. The church features marble and cast-iron floors, and the side altars are dedicated to Saint Nicholas and Saint Catherine the Great Martyr. The architectural dominant is a four-tiered bell tower, built between 1902 and 1904, designed in the style of brick neo-Baroque.

The miraculous icon was carried in processions through the villages of the Birsky, Ufa, and Sarapul districts. In 1910 and 1914, the church and monastery were visited by Grand Duchess Elizabeth Feodorovna Romanova. With the advent of Soviet power, the church was closed in 1934 and looted, and the icon disappeared. The building was used as a warehouse, tavern, and bakery. In the 1970s, part of the village was prepared for flooding, but reconstruction saved the church and historical buildings.

In 1993, the charitable foundation "Nikolsky Church" was established, and in 1994, the Nikol-Beryozovsky Historical and Cultural Center. Valery Grigoryevich Teterov became the main initiator of the church's restoration. Over 10 years of restoration, many elements of the church were recreated, and a local history museum was opened on the second tier of the bell tower. Restoration work continues, including the cancellation of flooding plans and the creation of a museum-reserve.

Since 1994, celebrations in honor of Nicholas the Wonderworker and the Day of Slavic Writing and Culture have been held in the village. Solemn services are conducted in the church, exhibitions, performances by artists, and theatrical presentations are organized in the square. For several years, a bell ringing festival was held with the participation of bell ringers from various dioceses of Russia.