In the late 1940s, a significant part of the second wave of emigrants began to leave post-war Europe, heading to the USA, Australia, and Latin America. As a result, by 1950, a small but active Russian colony had formed in Peru, which decided to build an Orthodox church. A house was rented in the Jesus Maria area of Lima, and an iconostasis was arranged.

The Peruvian government set a condition for the construction of a non-Catholic church: the creation of a cultural non-profit association. Thus, on December 17, 1953, the Orthodox Cultural Association (Asociación Cultural Ortodoxa Cristiana) was founded, consisting of 55 members. At the initiative of Prince Alexei Chagadaev, fundraising began for the purchase of land and the construction of the church.

Hieromonk Seraphim (Fetisov), the head of the new parish, along with the board of the Association, organized various events such as lunches, dinners, and dances to raise funds for purchasing land for the church. This was successfully accomplished on June 18, 1954, after which fundraising for construction materials began. Donors came from the Russian, Syrian-Lebanese, and Serbian communities.

The head of the community of Saint Blessed Matrona of Moscow in Lima noted that the Russian diaspora in Peru is young, consisting of immigrants from post-Soviet Russia, Ukraine, and Belarus. Many of them left their countries during a time when the church was just beginning to revive, and having not had the chance to become churchgoers at home, found themselves in a Catholic country where it was difficult to gain knowledge about the Orthodox faith. However, among them were those who became the initiators of creating the Orthodox community, and many engaged in its life, with some even joining the parish management. They deserve credit for this good initiative.