The church dedicated to the Iver Icon of the Mother of God, with chapels in honor of the Moscow saints and Saint Nicholas the Wonderworker, as well as the martyr Empress Alexandra, was laid on October 13 (25), 1899, in memory of the coronation of Emperor Nicholas II.

Its construction lasted three years, funded by Oryol railway workers with the support of the Moscow Society of Banner Bearers. The building was designed by architect N.I. Orlov in the 'Russian style.' In the last year of construction, it was necessary to take out loans. The works were overseen by the talented engineer F.P. Stepanov. The main altar of the church was consecrated in October 1902. In 1903, Nicholas II donated 1,000 rubles to pay off debts incurred during construction, and it was only in 1906 that the debts were fully settled. The church, built of red brick, was considered one of the most beautiful in Oryol.

In 1923, the church was closed and repurposed for a railway school. Later, it housed a clinic and a kindergarten. During the war, the building suffered significant damage. After the liberation of Oryol from the German-fascist invaders, the partially ruined building was used as a warehouse, a kerosene shop, and a glass container collection point. In 1990, the church was returned to the community of believers, and in 1992, after reconstruction, the main altar was consecrated. In 2005, a church in honor of the icon of the Mother of God 'The Seeking of the Lost' was built and consecrated at the Naugorsk cemetery in Oryol, becoming part of the Iver Church.