The memorial wing of the estate of V.E. Borisov-Musatov opened its doors in April 2000. The idea of creating a museum in the house at Volskaya 33 in Saratov, where the artist lived, originated back in 1922. This initiative was proposed by his sister Agrippina Elpidiforovna Nemirova, née Musatova.

The wing and the two-story house, which make up the urban estate of Borisov-Musatov, were included in the list of historical and cultural monuments of Saratov province in the mid-1920s. This was done by local historians and employees of the A.N. Radishchev Museum, as well as inspectors for the protection of monuments A.V. and V.V. Leontiev. Thanks to them, photographs of the wing from the 1920s to the early 1950s have been preserved. However, in the 1930s, the artist's name was officially forgotten, and his work was labeled as 'bourgeois and decadent.' For a long time, the creation of a museum was impossible, and communal apartments were located in the former estate of Borisov-Musatov. Only a small wooden wing miraculously survived.

In the 1930s, the construction of a large furniture factory began, with walls that came close to the wing, destroying the old buildings and garden. During the 'thaw' period, Musatov's name became popular again, and interest in his personality and work increased. In 1970, the 100th anniversary of his birth was celebrated, and in 1973, major exhibitions of his works were held in Moscow and Saratov. Beloglinsky Street in Saratov was renamed in honor of V.E. Borisov-Musatov. However, the question of creating a museum was never raised. In 1979, a book by Konstantin Shilov titled 'My Colors, Melodies' was published by the Volga Book Publishing House, dedicated to the life and work of the artist. Thanks to the active efforts of the writer, the wing, which by that time had become very dilapidated, was saved from demolition.