The Church of St. Sergius of Radonezh at Isakogorka Station was opened primarily for the workers of the railway hub. As early as 1895, shortly after the construction of the railway began, a mobile church was already operating here.

A few years after the railway was put into operation, the construction of a wooden church began. The residents of Isakogorka chose a high and dry place called "kulebyaka" for it, and within a year, the church was built. In 1902, the silence of the taiga forests and swamps was broken by the ringing of the bells of the new church, consecrated in honor of St. Sergius of Radonezh.

The church attracted attention with its appearance: a tall bell tower, a roof with several levels, large windows with stained glass, and large crosses embedded in the walls. Birch trees were planted on both sides of the road leading to the church. The church was always crowded: it was visited not only by railway workers but also by peasants from the surrounding villages of Zaruchye, Isakova Gora, Valdushki, Lakhta, and Kholm.

In 1924, the church was closed, and it was turned into a gym, and later into school workshops. In 1930, a store was opened here, which the faithful boycotted for a long time in protest against the desecration of the church. Only after almost 70 years was the church restored through the efforts of the faithful and priest Father Vasily Gangur, who became its first rector. It was impossible to recreate the former appearance and interior decoration, but the main thing was that parishioners could once again pray in the church.

On August 7, 1994, the rector of the cathedral, Archpriest Vladimir Kuziv, consecrated the church's crosses, and the first liturgy took place on October 15, 1995.