Bolshoy Tolmachyovsky Lane got its name due to the settlement of translators, or tolmaches, who appeared in Zamoskvorechye as early as the 14th century. In I.M. Snegirev's book "Moscow. Detailed Historical and Archaeological Description of the City," it is mentioned that since Zamoskvorechye was mainly inhabited by Tatars, their translators settled in the area of Tolmaches (Tolmach settlement), who came with ambassadors and baskaks from the Horde, as evidenced by the charter of Grand Duke Vasily the Dark.

In the early 17th century, Bolshoy Tolmachyovsky Lane was called Nikolayevskaya Street due to the wooden church of St. Nicholas in Tolmaches. The street was lined with wooden houses, and its architectural appearance remained almost unchanged throughout the 18th century.

The situation changed with the appearance of the large estate of the Demidovs at the end of the 18th century. Merchant families began to settle in the lane and build manor houses. Many of them burned down in the fire of 1812, as they were wooden. However, after 1814, they were restored in stone, in the Empire style characteristic of Moscow after the fire. One such house is the residence of ensign Yekaterina Sergeyevna Lobkova, built in 1817 and now beautifully restored.

The two-story stone house with a wooden mezzanine faces Bolshoy Tolmachyovsky Lane. The house had entrance gates and a gate in the Empire style. In the 1850s, additional wings were added to the house from the courtyard side. Later, the mezzanine was remodeled, creating a loggia with a view of the Church of St. Nicholas in Tolmaches. Mezzanines with loggias were rarely arranged in Moscow houses.

The architecture of the house is executed in the style of Moscow Empire. In the center of the house is a risalit with a pilastered portico on the first floor. The lower tier is decorated with rusticated stones, and the three windows of the risalit have a keystone-shaped crown. Above two windows on the second floor are elegant sills. Between the pilasters is Empire-style decor. Above the cornice of the mezzanine rises a three-tiered attic, and the ends of the loggia walls are finished with consoles supporting the architrave. Everything is done strictly and elegantly. The house harmoniously fits into the historical architectural environment of Zamoskvorechye.