The history of the historical part of the building of Rostov Lyceum No. 33 dates back to pre-revolutionary times when it belonged to the Rostov sculptor, artist, and graphic designer Ivan Mikhailovich Trofimenko. The building was constructed in the early 20th century as an income house and generated a decent income. The first owner was retired lieutenant Kipman, a representative of the large partnership "Georges Bloc," which dealt in the sale of bicycles, knitting and sewing machines, scales, adding machines, cash registers, boxes, and other goods.

In 1909, the building received the name we are familiar with today as an income house. At that time, the "Georges Bloc" company left the market due to financial difficulties, and the house passed to Ivan Mikhailovich Trofimenko. He owned a printing house on Dmitrievskaya Street (now Shaumyana) and moved it to the first floor of the new building, while the second floor housed a paper factory of the partnership "Colorit." About 30 people worked at the factory.

In March 1913, a severe fire occurred in the building, destroying the second floor and the roof. The factory's goods were rendered unusable, and the equipment was burned, but the stone walls withstood. The property was insured with the insurance companies "Russia" and "Salamandra," which allowed Trofimenko to quickly restore the building and add a third floor. The landlord's income after the reconstruction increased from 910 to 2580 rubles per year.

Rostov-on-Don needed specialists knowledgeable in natural and applied sciences, and the city council discussed the opening of a second real school. In February 1914, the council members considered proposals from 13 landlords willing to accommodate the school in their buildings. Most chose Trofimenko's house, agreeing to pay 7000 rubles per year for rent. Some deputies criticized the location for its distance from the center and proximity to factories and shelters, but the decision was made in favor of Trofimenko's house.

The contract obliged Trofimenko to expand the premises with an annex or by reallocating areas occupied by shops, remove the meat shop, and not rent out spaces for the sale of fragrant or flammable goods. He was to provide the school with a free yard of 10×10 fathoms, demolish the building, and asphalt the area.

The industrial site was transformed into a building for educational purposes, where 140 boys lived on a full board. The second real school existed until the arrival of Soviet power, after which it was closed. In 1928, a women's gymnasium run by Kotlyarova and Sennik opened in the building, where 190 girls studied. It was later replaced by labor school No. 4, which effectively served as a labor colony for minors.

After World War II, the former income house housed secondary school No. 33, which is now called "Physical and Mathematical Lyceum No. 33 named after the Rostov People's Militia Regiment." In the 1970s, an annex was added to the historical building, but it is still considered a cultural heritage site of regional significance.