The Pyshma settlement was founded in the mid-17th century. The exact date of the church's founding is unknown, but historians suggest it appeared soon after the construction of the first peasant huts. The first mention of the Pyshma church dates back to 1680, and it is believed to have been wooden. The church served the faithful for about a hundred years until it was dismantled due to dilapidation.

The construction of a new stone church began in 1808. Parishioners actively participated in laying the first stone and in the main construction work. The church was two-storied and had two altars, built in the style of Siberian Baroque. The lower altar was consecrated in honor of the Epiphany of the Lord in 1820 and was equipped with stoves for winter services. The upper floor was considered summer or cold, and since 1842 it was named after Saint Nicholas, Archbishop of Myra in Lycia, the Miracle Worker. Ten years later, the church acquired a stone fence with metal grilles. The parish of the Epiphany Church included residents of Pyshma and neighboring villages such as Sovinaya, Chernysheva, Kochevka, Tupitsinskaya, Shipunova, Ust-Derneyskaya, Kruchinina, and others.

A special fact is associated with the icon of Saint Great Martyr Paraskeva, which appeared in the first half of the 19th century. The image was found by a resident of the village of Sovinaya (now Savino) on the Pyshma River. The icon was brought to the Epiphany Church with solemn prayers, but soon it disappeared and was found again on the same riverbank. After several attempts to return the icon to the church, it was found again by the river.

According to legend, the Holy Virgin appeared to one of the locals in a dream and instructed him not to move the icon but to build a church at the place of its finding. The covenant was fulfilled: first, a chapel was built in Sovinaya, and then a stone church, where the icon remained forever.

The Church of the Epiphany of the Lord was closed by the Bolsheviks in 1935. Church valuables were confiscated, bells were melted down, and the fence was dismantled. The church building was used for the needs of the working settlement of Pyshma: it housed a warehouse, a ski base, the cinema 'Kolos', and later a museum of the history of agriculture and peasant life.

In the early 1990s, an Orthodox community was established in Pyshma. In 1995, local authorities transferred the second floor of the Epiphany Church to the Russian Orthodox Church, and since then services have been held there. The first floor is still occupied by the museum, and the neighbors coexist without conflicts. Believers joke: 'Better less than nothing,' as the altar is on the second floor, closer to Heaven.

Every year, the prayer room is adorned by the efforts of parishioners and donors. Necessary utensils and furniture are appearing. It is still too early to talk about a complete reconstruction of the Epiphany Church, as the lower chapel, bell tower, and central dome need to be restored. When this will happen is known only to God.