In the mid-17th century, the Assumption Women's Monastery was founded in the Alexandrovskaya Sloboda. In 1662, the Reverend Korniliy of Alexandrov became its abbot, under whose leadership the monastery developed: the number of nuns increased and funding was allocated from the treasury. In September 1678, Tsar Fyodor Alexeyevich visited the monastery during a pilgrimage. In the same year, a plot of land was allocated in Moscow for the courtyard of the Assumption Monastery. The building of the courtyard, adjacent to the refectory of the Apothecary Order, was constructed around the 1680s.

The courtyard building is one of the few surviving civil structures from the pre-Petrine era and is a typical example of a residential house from the late 17th century with three-part stone chambers. Over time, its facades suffered: windows were enlarged, and the second floor was partially rebuilt. In 1978, restorers I.I. Kazakevich and V.V. Putiatina carried out restoration work, returning the original appearance of the recessed windows with arched tops on the first floor. The building received a high four-pitched roof with attic projections, and decorative elements of the facade, such as inter-floor ties and cornices, were recreated, restoring the chambers' features from the 17th century.

The two-story building is oriented with its end towards the street, opening its grand facade to the courtyard. Previously, the facade was adorned with a red porch (now lost) leading to the second floor, where the door opening and traces of the porch's attachment are still visible.

The layout of the interior spaces was the same on all floors, including a deep basement: the central part was occupied by a vestibule with a cylindrical vault, while two large chambers with vaulted ceilings and arches were located on the sides (the vaults on the second floor have not survived). Thus, the vestibule divided the house into two parts with different purposes. Access to the basement was via an external staircase under the porch, which is now located in a pit.

Until 1917, the chambers belonged to the courtyard of the male monastery of the Holy Assumption Florishchev Desert. Currently, the building houses offices.