The history of the estate on Petrovka begins in the second half of the 19th century, although the main house was built a century earlier, presumably by a student of M.F. Kazakov. Kazakov's albums feature three student projects, including this one, indicating the master's high regard. The house was reconstructed from an older building that faced Petrovka end-on, which explains the asymmetry of the wings.

The first owner of the estate was merchant Kiryakov. The territory included a large pond surrounded by a vegetable garden and greenhouses. Kiryakov traded in seeds and owned textile factories, was an "eminent citizen" according to a charter from 1785, and was related to merchant Gubin, whose estate was indeed built by Kazakov.

In the 1830s, the estate was acquired by collector P.F. Karabanov. Mikhail Pogodin described his collection as a vast assembly of rarities, including vessels, bowls, medals, and manuscripts. Karabanov was acquainted with many notable figures of his time and compiled their biographies. He also published a list of Moscow mayors and transferred his collection to the government. After his death in 1851, his works on Russian history were published.

The estate also belonged to Prince M.A. Obolensky, and later it housed the Mariinsky School. In the late 1880s, clinician K.M. Pavlinov settled in the house. In August 1892, the first dental school in Moscow opened in one of the wings. In 1908, the Third Moscow Dental School and the First Moscow Mechanical Treatment Clinic of the Tsander Institute were located here.

The clinic lasted a long time and became a physiotherapeutic polyclinic during the Soviet era. In the years of perestroika, a medical cooperative "Health" opened in the house, which, according to advertisements, did not charge elderly and sick people. Currently, the building houses the Insurance Company of Law Enforcement Agencies.