The monastery was founded in 1634 by the nobleman Peter Glyadkov in honor of the Oran Icon of the Mother of God. Since 1866, it has been a communal men's monastery of the 1st class.

On the night of August 17 to 18, 1918, 15 monks of the Oran monastery, its abbot Archimandrite Augustine, and the rector of the Church of the Kazan Icon of the Mother of God, Nikolai Orlovsky, were shot on Mocalny Island, located on the Volga River near Nizhny Novgorod.

In 1920, the monastery was closed. From 1942 to 1949, a camp No. 74 of the NKVD of the USSR operated on its territory, where prisoner-of-war officers from Germany, Finland, Hungary, Austria, Romania, Italy, and other countries were held. According to some reports, their number reached 12 thousand people. Among the prisoners was also German Field Marshal Friedrich Paulus.

The monastery was revived in 1993. In August 2004, at the invitation of Bishop Georgy, Hieromonk Nektary Marchenko arrived to restore the monastery. He blessed the lighting of an unquenchable candle before the image of the Vladimir-Oran Icon of the Mother of God and to read the Akathist daily. On December 27, 2005, the Holy Synod appointed Hieromonk Nektary as the abbot of the monastery at the request of Bishop Georgy.

By the summer of 2009, all three churches of the monastery were whitewashed, and the brotherhood building was repaired. A brick fence was built around the monastery, and the main gates were installed. In June, a study of the bell tower's foundation was conducted, and funds were raised for its construction.

On September 21, 2011, on the feast of the Nativity of the Most Holy Theotokos, Archbishop Georgy consecrated the church in honor of this event. On September 8, 2012, Metropolitan Georgy consecrated the cathedral church in honor of the Vladimir Icon of the Mother of God. On December 15 of the same year, he consecrated the church of St. Athanasius, Patriarch of Constantinople, located in the basement of the cathedral church.

On December 12, 2013, Metropolitan Georgy consecrated the church in honor of the holy apostles Peter and Paul, as well as the new monastery bell tower.

On August 26, 2014, Metropolitan Georgy laid the foundation for a church in honor of St. Nektary of Pechersk. On November 26, 2016, he consecrated the gate church in honor of St. Nektary of Kiev-Pechersk.