In 1919, Vladimir Mayakovsky moved into a room on Lubyanka Passage. Before that, since 1918, he had lived with the Briks in Poluektov Lane, but after another quarrel with Lila Brik, he began looking for his own place. His longtime friend Roman Jakobson, a well-known linguist and member of the OPOYAZ group, helped him with this. The Jakobson family lived on the third floor of N.D. Stakheev's apartment building, and Roman moved to the fourth floor, after which he offered Mayakovsky a room in the apartment across the hall. The former owner of the apartment, Y. Balshin, fearing overcrowding, filled the rooms with acquaintances.

Stakheev purchased the lot from I.A. Romeiko in 1897 and immediately began construction, commissioning the project to architect M.F. Bugrovsky. The room on Lubyanka Passage became Mayakovsky's second home, where he wrote and kept his manuscripts. It was here that he took his own life on April 14, 1930. V.P. Kataev described how Mayakovsky divided his life between Vodopyan Lane and Lubyanka Passage, where he had a small bachelor room.

The room on Lubyanka Passage was small, only 11 square meters. After moving to Taganka, Mayakovsky kept this room as a study and meeting place. It was here that his fateful conversation with V.V. Polonskaya took place, which ended in tragedy. Polonskaya recalled how Mayakovsky loved to spend time in his room, sitting at his desk or standing by the fireplace.

This place became particularly famous due to the poet's death, which Polonskaya described in her memoirs. On April 14, 1930, Boris Pasternak in "The Protective Certificate" described how the news of Mayakovsky's death shocked the people gathered at the house on Lubyanka Passage. Pasternak called Olga Petrovska, who recalled how Pasternak informed her of the tragedy and how she hurried to the scene.

Until the 1970s, the building remained residential, and local residents remembered Mayakovsky. His room was sealed and served as a branch of the Museum-Apartment on Gendrikov Lane. In 1974, the building was vacated, and the museum was moved here. In 1989, Mayakovsky's house turned into a unique installation, immersing visitors in the poet's world. However, in the summer of 2013, the museum was closed for repairs.