The museum-laboratory of Evgeny Konstantinovich Zavoysky was opened in September 1997. It was in room No. 246 of the main building of Kazan State University that Zavoysky first recorded signals of magnetic spin resonance in the world in 1944. The idea of recreating the setup to observe the effect of radio frequency field absorption in a substance, when the radio frequency field is perpendicular to the magnetic field, received full support from corresponding member of the USSR Academy of Sciences and head of the department of magnetic radio spectroscopy S.A. Al'tshuler. This led to the creation of the museum-laboratory.

Significant preparatory work was carried out before the museum's opening. For 15 years, searches were conducted in libraries, archives, and museums, as well as in research institutes and universities in Kazan and Moscow. In particular, research was conducted in the collections of Kazan State University, the Kazan branch of the Academy of Sciences, the P.L. Kapitsa Institute of Physical Problems, the USSR Academy of Sciences, Moscow State University, as well as in the Zavoysky family and the National Archive of the Republic of Tatarstan.

Memories of Zavoysky's colleagues and contemporaries were collected, including professors from Kazan University S.A. Al'tshuler and B.M. Kozyrev. Important accounts came from his relatives, daughter Natalia and brother Vyacheslav. The search for authentic instruments that Zavoysky worked with was conducted in various institutes and schools in Kazan, as well as at factories and among private individuals.

For the 50th anniversary of the discovery of the electron paramagnetic resonance effect at Kazan University, an exhibition of physical instruments from the 19th and early 20th centuries was organized, including a functioning setup for magnetic resonance described in Zavoysky's laboratory notebooks.

These materials generated great interest among participants of the international congress "AMPERE," which took place in Kazan in 1994. Nobel laureate Professor Hahn was impressed by the collection of instruments, which is rarely seen even in the West. Scientists proposed to create the Zavoysky museum-laboratory at Kazan University. This proposal was supported by scholars from Russia, America, England, Germany, France, Japan, and other countries, as confirmed by the signed sheets stored in the museum.

However, it was only four years later that the decision was made to allocate room No. 246 for the museum, where EPR was opened.

Museum staff had to recreate the interior of a laboratory from the 1930s-1940s, restore the old oak parquet, windows, doors, walls, ceiling, and "Lutetia" type light fixtures, as well as laboratory equipment and physical instruments from the 19th and early 20th centuries, including those that Zavoysky worked on. Additionally, they continued to form the personal archive of Evgeny Konstantinovich and his scientific library.