In the historical center of Biysk, on Soviet Street, stands the majestic Assumption Cathedral, one of the main attractions of the city. On weekdays and holidays, its bell ringing spreads far around, inviting people to the service. The history of the temple is rich and eventful. Before its appearance in the city, there were already two Assumption churches. The first, wooden, was built in 1774 at the initiative of the commandant of the Biysk fortress, Colonel Pyotr Ivanovich Chetov, and existed until the early 1830s when it was demolished due to dilapidation. The second church, built by Colonel S.L. Bogdanov and consecrated in 1794, became the first stone building in Biysk. This church, known as the Cossack Cathedral, could not accommodate all the parishioners by the mid-19th century and was deemed unsafe in 1901. It was abolished in 1903, but as early as 1891, it was decided to build a new, larger cathedral. The funds raised by the parishioners were insufficient, but the situation was saved by merchant Mikhail Savelievich Sychev, who donated a significant sum for the construction.

The location for the new church was difficult to choose, but eventually, by the will of Sychev's wife, it was decided to build it next to the Cossack Cathedral. In 1892, the city council allocated land on Assumption Square, and soon construction began. The blessing for the laying of the church was received in 1897, and the construction was carried out according to a project in the Russian-Byzantine style. The church was consecrated in 1903, and its first rector was Archpriest Vladimir Dagaev. By 1908, the church was well-equipped with church utensils and had a unique library. Several educational institutions operated at the church, and it oversaw a house church.

In 1918, the church received the status of a cathedral, but in 1932 it was closed and used as a grain storage facility. The revival of the church began in 1947 when a parish community was registered. In the post-war years, the Assumption Church remained the only functioning church in the area. In the 1950s-70s, it faced the threat of closure, but thanks to the efforts of parishioners and clergy, it was preserved. Since 1969, the rector has been Archimandrite Yermogen Rositsky, under whom significant restoration work was carried out. In 1994, the church became a cathedral, and in 1998 it received the status of a cathedral. The Assumption Cathedral remains a model of church architecture and a center of Orthodox faith.