At the intersection of Pyatnitskaya Street and Klementyevsky Lane stands a large five-domed church of St. Clement, standing out among other Moscow churches. It is considered the largest in Zamoskvorechye, and its main treasure is the completely preserved interior decoration from the 18th century.

The first mention of St. Clement's Church dates back to the Time of Troubles in Russia. On August 24, 1612, during the liberation of Moscow from the Poles, there was a Clementievsky fort near the wooden church, where the Cossacks of the Second Militia fought against the detachment of Hetman Khodkevich. The victory of the Cossacks played an important role in the liberation of Moscow. By the mid-17th century, the church was already mentioned as stone, and in 1720 it was rebuilt by merchant Ivan Komlenikhin. In 1756, a large-scale reconstruction of the church began, affecting the western part, the bell tower, and the refectory, financed by merchant Kuzma Matveyev. The project is attributed to various architects: Evlashev, Trezzini, Michurin, Yakovlev, Blanck, Rastrelli.

In 1762, the construction of the eastern part of the church, the main altar in the name of the Transfiguration of the Savior, began and was completed in 1774. The church included seven altars with seven iconostases, which was unusual for a parish church. In addition to the chapels in the church and the refectory, two chapels were consecrated in the choir. St. Clement's Church is an outstanding example of Moscow Baroque, decorated with stucco depicting cherubs, shells, and rocailles. Ornamental grilles are used both in the fence and on the church building. The seven-tiered iconostasis of the main church and the side iconostases are made in the same Baroque style.

In 1934, the church was closed for services. Although it was planned to be demolished for the construction of a kindergarten, this did not happen. The building became a storage for the Lenin State Library, whose staff preserved five of the seven iconostases and a significant part of the interior. In 2008, the library left the building, and restoration work began. The church was restored: a pavilion was recreated on the side of Pyatnitskaya Street, the iconostases were restored, the foundation was reinforced, brickwork, plaster, windows, stucco, roofing were restored, and new crosses were placed on the domes. The porch and part of the church fence were also restored.

In 2013, the church became a laureate of the Moscow government competition "Moscow Restoration" in the nomination "Best Restoration/Adaptation Project."