In the 1940s, a significant "Russian colony" emerged in this large industrial suburb, consisting of post-war emigrants from various corners of the Soviet Union. Among them were Russians, Ukrainians, Poles, Jews, and representatives of other nationalities. A considerable number of former Cossacks also settled here, forming the first Orthodox community. They gathered in a private home for joint prayers.

The Cossacks made banners, which later became part of the church parish established in 1948. That year, a particularly large number of Russian-speaking emigrants arrived in Argentina, including Father Timofey Soina, who was also of Cossack origin. He was the first to spiritually care for the local flock, conducting services in private premises until the church was built.

In 1950, the parish was visited by Archbishop Ioasaf, who had recently arrived in Argentina. After familiarizing himself with the parish's situation, he blessed the acquisition of a plot for the church's construction and appointed Father Nikolai Cherkashin as the permanent rector.

In 1951, a plot was purchased, and on March 2, 1952, Bishop Ioasaf solemnly laid the foundation for the new church, the main construction of which was completed in less than two months.

In the May issue of the magazine "Orthodox Word" for 1952, Archpriest Nikolai Cherkashin announced the upcoming event: on May 25, Archbishop Ioasaf would consecrate the new church in honor of Saint Hermogenes in the Russian Settlement of the city of Quilmes. All donors, church choirs from all churches, and all Orthodox compatriots were invited to this joyful event.

Saint Patriarch Hermogenes, who suffered martyrdom in the dungeons of the Chudov Monastery, did not fear to oppose the illegal secular authority of the Polish invaders, unlike many hierarchs of that time. He inspired the Russian people to create a people's militia, which ultimately expelled the Polish invaders.

By the time of the consecration in 1952, several icons painted by Father Nikolai Masich were already in the church. Father Nikolai Kolchev gifted the new church a piece of the tomb of Saint Hermogenes, brought from Russia. During the consecration, the rector of the church, Father Nikolai Cherkashin, was awarded by Bishop Ioasaf. The description of the celebration preserved in the Orthodox magazine conveys the atmosphere of universal joy and inspiration.