By the 1750s, this estate belonged to the Ober-President of the Main Magistrate Stepan Stepanovich Zinovyev, then passed to his brother, and in 1798, Prince Fyodor Baryatinsky acquired it from Chamberlain V.S. Vasilychikov. By 1806, a large wooden house with a mezzanine on a stone foundation and a two-story stone building along the alley were already standing on the estate.

In 1814, the estate was purchased by Guard Ensign A.P. Khrushchyov. The basement of the main house, the residential wing, and the old chambers from the early 18th century, which survived the 1812 fire, became the basis for a new estate, which was overseen by the Commission for Buildings under the direction of O.I. Bove. The Khrushchyovs were wealthy landowners and led a prominent Moscow lifestyle. A.P. Khrushchyov had 14 children, and the family remained close even when the children left the parental home. It is worth noting that A.P. Khrushchyov was related to the Naryshkins through his daughter Elizabeth. Her husband, Alexei Ivanovich Naryshkin, was the son of Privy Councillor and Senator Ivan Alexandrovich Naryshkin, the uncle of N.N. Goncharova. Ivan Alexandrovich was the godfather at the wedding of Natalia Nikolaevna and A.S. Pushkin. Pushkin was acquainted with his children, including A.P. Khrushchyov's son-in-law, Alexei Ivanovich. The Naryshkins lived nearby at Prechistenka, 16.

In the 1860s, the house on Prechistenka passed to retired Staff Captain D.S. Seleznev. D. Nikiforov mentions in his book "From the Past of Moscow. Notes of an Old-Timer" that the house from Khrushchyov was transferred with all its furnishings to merchant Rudakov, and then sold in the early 60s to D.S. Seleznev. The house was preserved in the same condition as during the Khrushchyovs, even the old paintings remained in their places. The Seleznev family owned the estate until 1906, when the last owner, daughter of E.D. Matveev, transferred it for an orphanage, the school of the Moscow nobility named after D.S. and A.A. Seleznev.

By that time, the estate was well-equipped. The administration of the orphanage rented out some premises and buildings. According to the 1908 census, the basement of the main house housed a storage room for boxes and wines, the first floor contained the orphanage itself with the headmistress's apartment. The mezzanine had rooms for the class lady and the hospital nurse. In the large wing along Khrushchyov Alley were the orphanage's kitchen, staff room, and hospital. The second floor housed the dormitory for the Mariinsky Institute. The musical pavilion of the estate housed an umbrella workshop and a hairdresser. Despite the diverse use, the estate retained its original appearance until 1935, when the Church of the Friday of Gododomska was demolished, and a secondary school was built in its place, partially occupying the estate's territory. During construction, the stone semi-rotunda in the garden was destroyed, and in the 1960s, the wooden musical pavilion at the corner of Chertolsky Alley was demolished down to its white-stone base, which was restored in 1986-1987.

After 1917, all buildings of the estate, except for the main house, were used for housing. From 1924 to 1931, the main house housed the Toy Museum, a library, and the Toy Faculty of the Moscow Technical School of Handicraft Industry.

Modern Purpose

In October 1957, a decision was made to create a museum in Moscow dedicated to the life and work of A.S. Pushkin. For this purpose, the former Khrushchyov-Seleznev estate was allocated, where large-scale restoration work was carried out for four years. On June 6, 1961, the museum on Prechistenka was opened.

All buildings of the estate, including the main house, have the status of architectural monuments of federal significance.