In the 17th century, on the expanses of the Volga, in the channels and arms, near Astrakhan, more than ten uchugs emerged. Nearby, there were usually settlements with economic buildings. Over time, fishing villages formed in these places, which still exist today. Kamyzyak, one of the uchugs, was gifted by Tsar Alexei Mikhailovich Romanov to the Kurakin princes, who populated it with exiles.

The formation of the Kamyzyak uchug is associated with the reign of Alexei Mikhailovich, but the year 1560, during Ivan the Terrible's time, is also mentioned. The church chronicle states that the name Kamyzyak comes from the Tatar word "kamys", meaning "reeds", which grew abundantly around the settlement. In 1722, Peter I visited the Astrakhan region, including the Kamyzyak and Chagansky uchugs, which later passed to the treasury and were rented out to Astrakhan merchants. In 1872, the renter Mukhanov moved the group from the village of Kamyzyak 20 versts closer to the sea, but the residents remained in their original place.

Since its founding, the village had three churches: in honor of the Smolensk Icon of the Mother of God, in memory of the Apostle Silas and Sildanya, and in honor of St. Nicholas the Wonderworker. They were built with donations from the owners of the uchugs and prosperous villagers.

Kamyzyak was considered a wealthy village. Academician Ozeretskovsky noted that it had wooden churches, one stone church, and forty merchant houses.

The first church in Kamyzyak was built in the 16th century, the second, a stone one, in 1760 and existed until 1804. In the same year, a new church made of white brick in honor of St. Nicholas the Wonderworker was erected in the center of the village.

In the decree of the consistory from 1770, it was ordered to dismantle the dilapidated Nicholas church and build a house for the clergy from its materials. In 1839, a new church was built, and in 1868 it was expanded by adding an annex in honor of the holy apostles Peter and Paul.

In 1875, a church parish school operated in Kamyzyak, where 15 boys and 2 girls studied. In 1975, it was mentioned that there were three churches in Kamyzyak, one of which, made of white stone, was located at the former cemetery and was dedicated to St. Nicholas the Wonderworker. During the construction of the fire station, remains with church utensils were discovered. A wooden church for the poor was located at the site of the current cemetery, where clergymen lived. Nearby was a garden called "popovskij".

In the center of the village, where a monument to those who fell during the Great Patriotic War now stands, there was a large park. At the beginning of 1917, a church of the Icon of the Unburnt Bush was opened there, built with donations from residents from red bricks with gilded domes. The church was destroyed between 1924 and 1930. According to the stories of the locals, it was demolished for four years, led by the son of a church servant. The bells were sent for melting, and the bricks were used for building a school and sold to Kalmykia. The foundation of the temple remained in the ground.

Next to the church was a two-story building, where the church parish school was on the first floor, and the clergy lived on the second. This building has survived to this day and is called "Church Lane". Now, near the park, a new church of the Smolensk Icon of the Mother of God, the Odihria, is being built. The construction of the brick temple began in 1997 and was completed in 2008. The temple was erected on the site of the church destroyed during the Soviet era.