The village of Bolshie Kemary, located in the Perevozsky district, is known for its monument of urban planning and architecture of federal significance, the Sign Cathedral. The main altar of the cathedral is dedicated to the Sign of the Mother of God, while the warm chapels are dedicated to St. Sergius of Radonezh and Archangel Michael. In the cold part of the church, there are chapels in honor of the Lord's Robe and St. Demetrius of Thessalonica. According to legend, a small part of the robe was acquired by Sergey Ivanovich Miloslavsky in the late 16th or early 17th century and was passed down to the Bakhmetev family. In 1827, a chapel was established in honor of this relic. The object dates back to 1701 and the first half of the 19th century. The documents for its acceptance into state protection have numbers 1327 and 176.

According to the book 'Holy Blessed Sergius and Nizhny Novgorod Land', the cathedral in honor of the Icon of the Mother of God 'Sign', built in 1701, is a decoration of the village of Bolshie Kemary. The church is located on a hill and can be seen from afar, even from the Perevoz-Ichalki highway. Previously, several altars were consecrated here: in the warm refectory part, in honor of St. Sergius of Radonezh and Archistrateg Michael, and in the cold part, in honor of the Lord's Robe and St. Demetrius of Thessalonica. The village of Kemary, founded in the 16th century, belonged to the boyar Morozov, and later to Prince Boris Alexeyevich Golitsyn, the tutor of Peter I. In the 19th century, when the settlement of Malye Kemary appeared nearby, the village began to be called Bolshie Kemary.

The architectural appearance of the Sign Church dates back to the late 17th and early 18th centuries. The refectory part was expanded for additional chapels. In the first half of the 19th century, an extension with a dome and a three-tiered bell tower was added to the church from the west side. In the early 20th century, the main building and the old part of the refectory were covered with roofing iron to avoid restoring the brickwork and decorative elements.

In 1887, the Golitsyn estate was acquired by landowner Aglaida Lukinichna Tomanovskaya, who surrounded the estate with berry bushes and an orchard. Near the church is the grave of Dmitry Grigoryevich Bakhmetev. The last owner of Bolshie Kemary was architect Vladimir Petrovich Tseidler, who arrived in Nizhny Novgorod in 1894 to participate in the preparation of the All-Russian Exhibition of 1896.

Today, the church is inactive and is in an emergency state, despite its status as a monument of architecture of federal significance. The altar part was lost during the Soviet era, and in 2008, weather conditions destroyed all the domes of the church, including the bell tower.

In the directory 'Monuments of Urban Planning and Architecture of the Gorky Region' edited by V.P. Fadeev, published in 1980, it is noted that in the early 20th century, the building and the old part of the refectory were covered with iron, and the facades with brick details were covered with smooth iron sheets, which led to further destruction of the brickwork.