The Epiphany Church, built between 1687 and 1695, is a refectory-type temple. A high two-light cube adjoins an apse with three semicircles, as well as a two-column refectory with an altar dedicated to the Vladimir Mother of God from 1691, a porch with a residential chamber, and a bell tower. The church is connected to the apse and refectory by three-arched openings. Nearby is the chapel of Saints Peter and Paul. The bell tower is designed in the "octagon on a square" style with a tent-like top and has been rebuilt multiple times. In the 18th century, salt industrialist M. Surovtsev, whose estate was nearby, allocated funds for its reconstruction. The facades of the church are decorated with zakomaras, window frames in the shape of keel-shaped kokoshniks, multi-tiered portals, and cornices made of molded brick. The facade decor is complemented by multicolored tiles on the bell tower, cube, and drums. A distinctive feature of the Epiphany Church is the abundance of relief tiles depicting pelicans, peacocks, and turkeys.

The church is unique in that it has preserved a carved wooden iconostasis with icons of Stroganov painting from the 18th-19th centuries. The iconostasis contained about 75 icons, most of which have survived and been restored. The site for the church was chosen at the founding of the city, where a wooden church in honor of Saint Clement IV previously stood. In 1635, the wooden church burned down but was quickly restored. After the fire of 1673, it was decided to build a stone church, which was laid in 1687. The altar in honor of the icon of the Vladimir Mother of God was consecrated in 1691, and the main church of the Epiphany in 1695. In 1770, an altar in honor of Saints Anthony and Theodosius of the Caves appeared. The original bell tower was low, but in the second half of the 18th century, it was raised with funds from M. Surovtsev to install a clock. Due to insufficient foundation strength, the bell tower settled, and in 1938 it was dismantled. The bell tower housed 16 bells, with a total weight of 729 poods 22 pounds. After the church was closed in the 1930s, the bells were thrown down and sent for melting. Only two fragments with the inscription of craftsmen Yakov and Ivan Lodygins have survived.

The iconostasis was made in the second half of the 18th century, but it included icons from the old 17th-century iconostasis. The main relic of the church is a triptych with the image of St. Nicholas the Wonderworker, gifted by Ivan the Terrible in 1552. At different times, the icon was located either in the summer Trinity Cathedral or in the winter Exaltation of the Cross Cathedral. The parish was liquidated in 1934, and the building was transferred to a museum. During World War II, the church was returned to the Russian Orthodox Church, and it remained active until 1962. In 1944, the tent of the bell tower was restored according to the project of architect F.M. Toltsiner, modeled after the tent of the Transfiguration Church. The restoration was done in wood. Subsequently, the bell tower was returned to its original appearance, and the church was again transferred to the local history museum.

Since 1989, the Epiphany Church has housed a branch of the Solikamsk Local History Museum, "Museum of Ancient Russian Art," which features a collection of icon painting and a restored iconostasis. In 2005, the church was restored; however, the sponsor insisted on the installation of golden domes, which stand out against the green domes of other churches. The crosses were also replaced with "Finnish stainless steel" ones. The church is a monument of history and architecture of federal significance.