The village of Arsk, located by the Seld River, was founded in 1649 as a military settlement for Cossacks relocated from the city of Arsk in the Kazan province. In 1651, a wooden Epiphany church was built here. In 1770, collegiate assessor I.S. Pustynnikov constructed a stone church of the Epiphany with an altar dedicated to the Most Merciful Savior.

The construction of the temple is distinguished by three main periods. The temple itself and the eastern part of the remaining refectory were built in 1770. The separate bell tower was erected in the 19th century. Soon after, the arches of the first tier of the bell tower were bricked up, and it was connected to the temple by extending the refectory to the west. The church, designed in the traditional three-part composition, is located on the western outskirts of the village in an open flat area, one kilometer to the right of the road near Ulyanovsk.

Built in 1770, the church follows the traditions of Russian architecture of the early 18th century and is characterized by monumental simplicity of forms and conciseness of volumetric solutions. The dimensions of the building are 30 by 8.5 meters. The bell tower, constructed in the 19th century, is an interesting example of classicism for the province.

During the Soviet era, the building was used as a storage facility for agricultural equipment of the Alexander Matrosov state farm in the Ulyanovsk region. For a long time, it remained abandoned and gradually deteriorated. Currently, the church has been restored and is one of the attractions of the Ulyanovsk region.

The Epiphany Church of 1770 has been included in the register of historical and cultural monuments by the Government of the Ulyanovsk region as an object of regional significance.