The Chapel of Luka Voyno-Yasenetsky at the main city hospital is a significant monument of church architecture from pre-revolutionary Azov. It was built in 1895 thanks to the funds of Azov resident Mikhail Golovsky and the financial support of wealthy townspeople. The construction took only one year. In 1912, the chapel was consecrated and functioned until the arrival of the Bolsheviks.

In the 1920s, after the Bolsheviks came to power, the chapel was partially destroyed, losing its cross and dome, and began to be used for the hospital's economic needs. In 2003, at the initiative of the rector of the Azov Icon of the Mother of God, Father Alexander, and with the active support of the hospital's chief physician Bridkovsky, entrepreneurs, and parishioners, the restoration of the chapel began. Old bricks were used for the restoration to preserve the original appearance of the building. On October 1, 2005, the chapel was reopened and consecrated by Archbishop Panteleimon of Rostov and Novocherkassk in honor of Saint Luka. It is now the only church building in Azov that has survived since pre-revolutionary times thanks to the efforts of the townspeople.