In the late 18th century, plot No. 11 on Sushchevskaya Street belonged to state councilor D. I. Kiselev. On its territory were a stone main house and several wooden service buildings. After the Moscow fire of 1812, in 1817, Kiselev sold the estate to the state for the placement of the Sushchevskaya police station with a fire depot. In the mid-19th century, the main house was rebuilt according to the design of architect Mikhail Bykovsky. Buildings for police and fire services, as well as a detention house, appeared on the site. At this time, a fire tower was installed on the main house, which has survived to this day. A guard was on duty at the top of the tower, signaling fires by raising balls and flags, and at night, lanterns to inform citizens of the location of the fire.

In 1898, the first ambulance station in Moscow opened here and at the Sretenskaya police station.

The Sushchevskaya police station housed many well-known prisoners. In the 1870s, the abbess Mitrofanija, accused of forgery, was held here. In 1909, V. V. Mayakovsky was detained in the detention house, suspected of aiding the escape of female political prisoners. He wrote to his sister that the conditions were good and asked her to send books and drawing supplies. Pre-revolutionary newspapers reported on the escape of three peasants from the detention house through the cesspool.

The Sushchevskaya police station also destroyed copies of banned books. The last burning occurred in January 1888, when V. A. Gilyarovsky's book "The People of the Slums" was destroyed. Gilyarovsky recalled watching this process in the courtyard of the police station. Later, books were no longer burned; they were processed into pulp.

Today, the entire complex of the former Sushchevskaya police station has been restored and is protected by the state as a cultural heritage site. The Central Museum of the Ministry of Internal Affairs of Russia is located in the main house.