The house on Maloy Tolmachevsky Lane was formed as a result of several stages of construction. The first residential building on this site appeared in the mid-18th century as the main house of an urban estate, located deep within the courtyard. In 1806, when the owners were the noble Solovyovs, the mansion was rebuilt in accordance with new trends in classicism. The building acquired a proper rectangular shape, close to a square, and was topped with a cross-shaped mezzanine, giving it the pyramidal form characteristic of the early 19th century. The grand rooms were located along the western facade, while the eastern side featured lofts.

After the fire of 1812, the estate passed to the first guild merchant, honorary citizen of Moscow Alexei Semyonovich Medyntsev. His son, Alexei Alexeyevich Medyntsev, was a close friend of Pavel Mikhailovich Tretyakov, who lived nearby on Lavrushinsky Lane. In the 1860s, a two-story extension with two rental apartments was added to the main house from the side of Maloy Tolmachevsky Lane. The facade of the extension was designed in an eclectic style, and a staircase was placed between the old and new buildings. The territory also housed stone and wooden outbuildings.

After the Medyntsevs, the estate passed to merchant Mikhail Alexeyevich Remizov, whose son, future writer Alexei Mikhailovich Remizov, was born in 1877. He spent only the first years of his life in Tolmachi. In exile, shortly before his death, Remizov wrote the autobiographical story "With Cropped Eyes," where he described his small homeland. In the early 20th century, under merchant Ya.N. Kreynes, who organized production here, the density of the estate's construction significantly increased. New windows appeared on the courtyard side of the main house, somewhat disrupting the composition of the classical-style facade.

Today, the former house of Medyntsev-Remizov is a cultural heritage site. The building has been restored and plays an important role in the development of this part of Zamoskvorechye, forming the front of Maloy Tolmachevsky Lane. The ancient part of the house (the western part) is an example of classical architectural style and has partially preserved the composition and decorative elements of classicism. The volume facing the street is adorned with abundant decoration characteristic of eclecticism: figured attics crowning the facades, pilasters at the corners of the building, intricate inter-floor cornices, elegant niches of the first-floor windows, and other details. However, the main value of this house is its memorial significance, associated with the name of the writer Alexei Mikhailovich Remizov, who was born here.