Bolshaya Yakimanka Street is part of an ancient route connecting Kyiv and Rostov Veliky. It got its name from the chapel of Joachim and Anna in the Annunciation Church, located in Golutvina Sloboda. This chapel was popularly called "Yakima and Anna," which gave the name to the area Yakimanka. Since the 16th century, there were slobodas here where archers and various craftsmen lived, such as carpenters, coopers, and barrel makers. In the 18th century, the area began to be populated by minor officials, merchants, and clergy. Today, this street in the center of Moscow is adorned with numerous historical monuments.

At the corner of Bolshaya Yakimanka Street and 2nd Khvostov Lane (formerly Malaya Petrovskaya) stands the R.M. Glière Children's Music School. At the end of the 18th and beginning of the 19th century, a State Public Private School was built here. The stone building, which suffered in the 1812 fire, was repeatedly reconstructed: in 1815 for the Private Public School, in 1832 for the State Public Petropavlovsk School, in 1835 for the District Public School, and in 1842 and 1846 for the 2nd District School. Initially, the building had two floors: a lower stone and an upper wooden one. Later, a central mezzanine was added, which can be seen in a photograph from 1882.

In the early 20th century, the Moscow Educational District decided to build a new stone building for the 2nd Moscow City Public School. The project was developed in 1901-1902 by architect Alexander Alekseevich Nikiforov, who had been the architect of the Moscow Educational District since 1880. In 1905-1906, a new three-story stone building with a semi-basement and an attic was erected on the site of the old building. Basement premises for household needs were arranged under part of the yard. The building is located along the boundaries of the yard, with facades facing the street and the lane.

According to the property descriptions of 1906 and 1914, the semi-basement housed changing rooms, recreational and service rooms, as well as a boiler room. The first floor contained the inspector's apartment. On the second and third floors of the northern wing were spacious classrooms connected by wide corridors, while the eastern wing had smaller rooms. The fourth attic floor was initially occupied by teachers' apartments, and in 1914, it housed a hall, a physics lab, and an art classroom.

Since 1937, the building has housed the R.M. Glière Children's Music School, founded in 1933. Due to numerous renovations, the original layout has changed: large classrooms have been divided into smaller rooms. Currently, the third floor of the northern wing has an assembly hall, and the basement contains utility rooms. The building's facades, executed in eclectic style, have remained virtually unchanged. The western and northern facades have a clear system of horizontal divisions, while the western facade is adorned with a risalit and a turret. The Renaissance-style decor is highlighted in white, giving the building a festive appearance. The attic floor is decorated with profiled triangular pediments. The courtyard facades are designed more modestly, with inter-floor ties.

The building of the R.M. Glière Children's Music School is a vivid example of an educational public building from the early 20th century and still serves its educational function.