In 1828, the merchant's wife M.P. Arbusova acquired the property at the corner of Znamenka and the current Starovagankovsky Lane. She settled here with her husband Dmitry Nikolaevich, a lieutenant colonel and knight of the Order of Saint George, 4th class. Already on the 1829 plan, an Empire-style estate was depicted, oriented towards Znamenka. The two-story U-shaped main house stood along the street, behind it was a garden, and along Vagankovsky Lane were single-story buildings.

On both sides of the house stood a stone fence with gates, and the facades were painted yellow. The tall windows of the second, ceremonial floor were adorned with rhythmically repeating decorative elements: garlands with ribbons, profiled shelves above the keystone, and medallions with horns of plenty.

After 1833, the classical appearance of the estate changed due to the expansion of the building on Vagankovsky Lane for rental purposes. This form of the estate existed until 1884, when the northern part, the former garden, was separated by a solid fence and became a separate property. Here, architect B.V. Freidenberg built a two-story stone mansion for V.Ya. Lepeshkina, which was later raised by two more floors in the 1930s.

In 1909, architect N.N. Blagoveshchensky developed a project for a six-story apartment building for L.V. Shamsina, the facades of which faced Znamenka and the lane.

As for the Arbusov family, their fate can be traced until 1869. Merchant of the 2nd guild Nikolai Alexandrovich lived here with his five sons, then Dmitry and Konstantin Nikolaevich, and later only Dmitry Nikolaevich, who in 1869 was the elder of the Cross Exaltation Church.

It is likely that around 1884, the property was sold to V.Ya. Lepeshkina. According to the "All Moscow" directory of 1901, another Arbusova (Danilchenko), Anna, lived on Znamenka, but in another house, probably not related to this family.

Raisa Samoylovna Znamenская was the founder of the Society for the Establishment of a Shelter for Elderly Women with Medical Education. She was one of the first female students and women doctors in Russia, educated in Switzerland. In her youth, she was fascinated by socialist ideas and was part of a circle of revolutionary narodniks.

In 1868, she founded the first free Sunday school and children's library in Moscow. She participated as a doctor in the Serbian-Russian-Turkish wars of 1876-1878, managing the Belgrade military hospital. After the war, she engaged in private medical practice and lectured in Moscow.

In 1899, she established a society for the establishment of a shelter for women with medical education, which built a building at the Losinoostrovskaya station in the early 20th century. Soon, a church of St. Nicholas the Wonderworker appeared next to it, but unfortunately, neither the church nor the building has survived.