Before the 1917 revolution, this estate belonged to the famous and wealthy industrialist family von Vogau. Since the 1920s and to this day, it has housed the L.Ya. Karpov Scientific Research Institute of Physical Chemistry.

In 1878, Hugo von Vogau, head of the trading firm 'Vogau & Co.', acquired property at the corner of Vorontsovo Field Street and Krivogruzinsky Lane (now Obukh Lane). Later, he added the neighboring property. The old buildings were demolished, and in 1882, a new two-story house for the von Vogau family was built according to the design of architect Viktor Kossov. The initial project envisioned an eclectic style with elements of German Baroque, but ultimately a more concise neoclassical style was realized. The facade of the mansion was smoothly plastered, adorned with pilasters and buttresses, and topped with a cornice and stone parapet. Unlike the facade, the interiors were luxurious and exquisite, also designed by Kossov.

Most of the estate, located on the slope of the high bank of the Yauza River, was occupied by a landscaped park. The main avenue, lined with linden trees, led from the gates on Vorontsovo Field Street downwards, while a side avenue ran from the gates on the lane. In the center of the park, oaks grew, and at the bottom, there was a greenhouse.

Hugo von Vogau came from an ancient but impoverished German noble family. His father, Maximilian von Vogau, arrived in Russia in 1827 and within a decade became the owner of his own firm, founded with his brothers in 1840. The Vogaus traded in colonial goods and later invested in other sectors such as the paper-spinning, metallurgy, and cement industries, as well as banking. By the end of the 19th century, their enterprise had become a diversified conglomerate with enormous capital. Hugo von Vogau and his relatives were among the richest merchants and industrialists of the Russian Empire. He was an honorary citizen, a first-guild merchant, a commercial advisor, and was awarded the Orders of St. Stanislaus and St. Anna. He was also a member of the Moscow Architectural Society and a founder of the Committee for the Arrangement of the Museum of Fine Arts in Moscow, actively engaged in charity work.

The situation changed with the start of the war with Germany in 1914, which sparked anti-German sentiments and pogroms. In May 1915, one of the largest pogroms in Moscow occurred, during which Hugo von Vogau's mansion on Vorontsovo Field was burned to the ground. After this, the Vogau family decided to sell their enterprises and leave Russia.

The mansion remained in ruins until the early 1920s, when the former von Vogau estate was nationalized by the Bolsheviks and transferred to the Physical Chemistry Institute. In 1922, the house was restored and expanded to three floors according to the design of architect S.Ye. Chernyshev. The main laboratory building of the institute was located here, and apartments for staff were arranged on the top floor. In 1927, a semi-factory experimental station building in the style of constructivism was built, designed by Boris Iofan. Over time, the territory was developed with new buildings, but the central part of the park was preserved, although it has taken on a neglected appearance.

Unfortunately, since Soviet times and up to the present, the territory of the institute has been closed to visitors.