Malaya Yakimanka in Moscow got its name by analogy with the neighboring street Bolshaya Yakimanka, which, in turn, was named after the church of Joachim and Anna, known since the late 15th century. Unlike Bolshaya Yakimanka, the name Malaya Yakimanka has not changed since the 18th century. This area was sparsely built up and had craft settlements, where wooden structures predominated. In the early 18th century, Peter I banned stone construction in Moscow, as St. Petersburg was actively being built at that time. However, after his death in the mid-18th century, stone construction in Moscow resumed, and palaces and manor houses began to appear.

Among the residents of this street were merchants. For example, white-stone palaces were built on a plot belonging to the merchant's wife, Tatyana Yevdokimova. In the late 19th century, they passed to Ivan Vasilyevich Chetverikov, a cloth merchant, who expanded and rebuilt the house. In the mid-19th century, a mezzanine appeared on the house. After Chetverikov's death in 1863, his heirs rebuilt the house again. Over time, a merchant quarter formed here, between Malaya Yakimanka and Bolshaya Polyanka streets. Nearby was the estate of I.F. Jakobson, the Iver Sisterhood of Mercy, a church, a hospital, and a pharmacy. In the late 19th century, the estate passed to merchant Nikolai Osipovich Sushkin. After the 1917 revolution, the house became a communal apartment, where Sushkin's descendants lived until the mid-1940s. In 1934, a children's trauma clinic No. 20 named after K.A. Timiryazev opened nearby. After the eviction, various offices occupied the Chetverikov house, and since 1983 it has been almost vacant.

In 1987, the mansion was surveyed and a restoration project was prepared, which was not implemented. The house remained vacant and deteriorated for a long time. In 2003, restoration of the buildings and construction of a new wing for the Research Institute of Pediatric Emergency Surgery and Traumatology based at the 20th hospital began under the direction of Leonid Roshal. The estate of I.F. Jakobson and the territory of the former Iver community were used for this purpose. The institute did not require the estate building, but needed a garage and parking for ambulances. The problem was solved without demolishing the building, and the house was restored. Now, ambulances are constantly parked next to it.

Today, it is a beautiful historical and architectural monument that can be seen through a transparent fence. The facades are executed in the neoclassical style, the central part of the second floor is adorned with composite order pilasters, and the first floor is decorated with rusticated stone. The mezzanine is highlighted by ribbed pilasters, and the floors are separated by a profiled cornice. The house is painted in a soft turquoise color with white decorative elements and attracts attention with its harmony.