In 1904, a two-story stone building for the Women's School with a chapel was constructed based on the design of engineer N.L. Shevyakov. On June 9, 1905, the church was consecrated in the name of the icon of the Mother of God 'The Seeking of the Lost', and classes began at the school in the autumn of the same year.

The building features an interesting technical solution. The site dictated a complex, L-shaped form of the structure. The eastern part of the building houses the church, which stands out at the corner of Zatsepa Street and Bolshoy Strochenovsky Lane. The church is elongated along the street, with a setback filled by a covered porch and a square two-story tented bell tower.

The main volume of the church is crowned with a large dome on a high drum. A second, smaller dome rises above the altar area. The facades are decorated with majolica panels and ceramic tiles, including those on the bell tower.

From the courtyard side, a volume for stairs leading to the church and the main building of the school adjoined the church. In the wing of the building adjacent to the church, on the second floor, there was a recreation hall that could connect with the church, accommodating up to 800-900 people.

The architecture of the church is done in the neo-Russian style. The other parts of the school, although different from the church, also drew inspiration from ancient Russian architecture, evident in the high tent roofs and three tents marking the entrances to the building. Above the second-floor windows and on the attic, there were plaster inscriptions 'Moscow Society for the Promotion of Commercial Education' and 'Women's Commercial School', visible in a photograph from 1912. The turret with a tent housed the entrance to the school from Zatsepa with the inscription 'Glagolevsky Trade Classes'.

In 1905, a fence with gates appeared, and in 1909, a two-story building for the Preparatory Classes of commercial schools was constructed (architect A.U. Zelenko). This building adjoined the wall of the southern staircase extension of the church, forming a unified P-shaped volume. In 1912, the building for the preparatory classes was reconstructed according to the design of P.A. Zarutsky. After the revolution, the women's school building housed the G.V. Plekhanov Industrial and Economic College.

The chapel closed in 1925, and in 1926, its premises were reconstructed (project by V.I. Krauze). The iconostasis was dismantled, and the church space was divided into two floors. In 1930, the building for the preparatory classes was raised by two floors, and later the western wing of the former women's school was similarly raised.

By the mid-1980s, the church building suffered significant losses: the main dome was destroyed. During restoration work, the dome was rebuilt with a changed contour, and some decorative elements were partially restored. A porch was added to the stairwell of the former preparatory classes building, and a fence with an original design was constructed.

During the restoration, specialists restored the historical appearance of the complex of buildings, including lost decorative elements and historical inscriptions, and adapted the premises to modern educational requirements for students.

The site became a laureate of the 'Moscow Restoration-2016' competition in the nomination 'For the Best Organization of Repair and Restoration Works'.