The Holy Trinity Monastery in Tyumen is one of the oldest and active Orthodox monasteries in the city. Founded in 1616, it was originally named the Spaso-Transfiguration Monastery. After the revolution, its activities were suspended and resumed only in 1995.

The Trinity Monastery includes various types of churches: the cubic Trinity Cathedral, the refectory church of the Forty Martyrs, and the cross-shaped church of Peter and Paul.

The history of the monastery begins in 1621 when the Tyumen voivodes received a decree from the Kazan order to establish the Transfiguration Monastery. This year is considered its founding date.

Initially, the monastery did not have its own church, so in the summer of 1621, Hieromonk Avraamy from Rostov, builder Ion Likharev from the Vologda region, and cellarer Onufriy from Novgorod arrived. They were to build a church and other buildings. In 1622, a wooden heated Spaso-Transfiguration Church was erected.

In 1622, active construction was underway in Tyumen, and next to the Spaso-Transfiguration Church, the cathedral church of the Nativity of the Virgin, the parish church of the Assumption, the church of the All-Merciful Savior, the church of Archangel Michael and Saint Michael Malein, as well as the church of Elijah the Prophet appeared.

In 1705, a fire destroyed much of Tyumen, including the monastery, but the Annunciation Church remained unharmed. In 1706, Metropolitan Philotheus appealed to Peter I for permission to build a stone church in the monastery. Permission was granted, and in 1708, construction began, completed in 1715. The church was named the Trinity Church, and the monastery became known as the Trinity Monastery. This was the third stone building in Tyumen after the state granaries and the Annunciation Church.

In 1714, the construction of stone buildings was banned in Russia, but Metropolitan Philotheus obtained permission to erect the two-headed church of the Forty Martyrs, completed in 1717. After the ban was lifted in 1722, construction of the church of the apostles Peter and Paul began in 1726 and was completed in 1755. In 1724 and 1739, the abbot's buildings and stone walls of the monastery were constructed. In 1761, a Latin school was opened here. In 1842, a fire destroyed many structures, but the stone walls survived. Restoration took place in 1851 and 1853.

In the winter of 1923, the monastery was closed. Since 1922, the provincial archive was housed in its buildings, and from 1929, the premises were used by the City Economy Committee for cultural and public needs. In 1941, the monastery was transferred to the military formation of the Tyumen garrison. In 1946, several churches were demolished on its territory, and treatment facilities were built. In 1949 and 1950, a decision was made for restoration, and in 1960, the monastery was recognized as a monument of architecture of republican significance. In 1995, its activities resumed, and the surviving buildings were transferred to the Tobolsk and Tyumen diocese. In 2003, the first service was held in the Trinity Cathedral.