The staffing schedule of the Tashkent Preparatory Cadet School provided for the education of 100 cadets at state expense. After successfully completing the course, they were transferred without exams to the 3rd class of the 2nd Orenburg Cadet Corps.

Initially, the school was located in the building of the District Engineering Administration, but later a special building was constructed for the Tashkent Cadet Corps. The head of the school was Colonel I. M. Bonch-Bogdanovsky.

Since its founding, the school strictly adhered to the regulations and instructions for cadet corps of the Russian Empire. Nominally, it was subordinate to the Commander of the Troops of the Turkestan Military District, but in fact, it was under the jurisdiction of the chief of staff of the district.

The school accepted sons of officers from the Turkestan Military District, including the cities of Tashkent, Samarkand, Termez, Merv, Ashgabat, and others. Boys aged 9-10 years old were admitted to the first class.

On September 2, 1901, the new building of the cadet corps, built on the outskirts of Tashkent by the Salar River, was consecrated. It impressed with both its exterior and interior decoration. Spacious and bright rooms for classrooms, dormitories, a dining hall, and a recreation room testified to the careful work invested in its construction. On October 16, 1905, a church was consecrated, in the altar of which a portable iconostasis of Emperor Peter I was installed, gifted by Grand Duke Nikolai Konstantinovich and received from the Pereyaslavl Male Monastery.

On May 8, 1904, the school was transformed into the Tashkent Cadet Corps.

Classes in the corps, later renamed the military gymnasium, continued until the spring of 1918. After the 11th graduation, by decision of the new authorities, the corps was disbanded.

In 1920, a medical faculty of the Turkestan University opened in its building. In the 21st century, the 2nd clinic of the Tashkent Medical Academy is located here.