The Resurrection Cathedral in Cherdyn was laid in 1750 on the site of an old wooden church on one of the city hills. The consecration took place in 1754. Two chapels were added to the church, which has two levels of light: on the southern side in honor of Stephen of Perm in 1751 and on the northern side, the Nikolsky chapel, in 1785. The main building and the chapels were connected by a spacious refectory on the western side, to which a large bell tower was later added.

The architectural style of the cathedral is typical for the mid-18th century in provincial towns. It is characterized by modesty and the absence of lavish decor. The temple is crowned with five domes, four of which are placed on corner towers, while the fifth rises on two octagonal drums, the lower of which is open to the temple. The walls are impressively finished with semicircular completions with octagonal windows and crenellated cornices. The bell tower of the cathedral serves as the only architectural vertical in the city and is a landmark. The walls and vaults were painted by the famous Cherdyn painter of the 18th century, Leonty Protopopov. The painting on the northern wall, dedicated to the baptism of the inhabitants of Great Perm by Bishop Jonah in the 15th century, was particularly notable.

Currently, the painting is hidden under a layer of lime. The interior was adorned with a multi-tiered iconostasis, brought in the 18th century from the closed Pyskor Monastery, but it has not survived. From 1908 to 1911, the cathedral was significantly rebuilt: an expanded refectory, porch, sacristy, and new bell tower were constructed on a rubble foundation of red brick. Old decorative techniques, such as crenellated cornices and semicircular curves, were used in the facade design. The bell tower's ringing tier was decorated with paired columns and crenellated belts, and above it was an open circular platform. The image of the Savior Almighty was transferred from the old bell tower to the facade of the new part. After the revolution, the cathedral was used for worship until the early 1930s, after which the building housed a district House of Culture. The building is now transferred to the Perm diocese, and restoration of the temple has begun. In July 2008, 9 new bells were installed on the bell tower, the largest of which weighs 2.7 tons. The installation was led by the famous bell ringer from Arkhangelsk, Vladimir Marjanovich Petrovsky.