The Trinity Church in Vetluga was built in 1805 from stone, with a stone bell tower and fence. This large temple had unique features: sculptures of the four evangelists were installed on pedestals at the corners of its square base. The altars of the church are dedicated to the Holy Trinity, the holy evangelist John the Theologian, and the venerable Theodosius, the miracle worker of Totma.

The local historian D.A. Markov, in his work "On the History of Vetluga," published in 1922, wrote: "A little south of the Trinity Church stand two pairs of stone pillars, which are located on the site of two former wooden churches destroyed by fire in 1840." However, he was likely mistaken, as the wooden Resurrection Church probably existed until 1859, until the consecration of the stone one. It is known that on April 22, 1856, Vasily Rozanov, a famous philosopher and writer, was baptized in the Resurrection Church of Vetluga, as evidenced by a record in the metric books.

In the summer of 1890, a fire engulfed almost the entire city, severely damaging the Trinity Church, which was located in the center. By the early 20th century, the city had been restored. Trinity Square, the main trading square, was crowded, especially on Saturdays and during fairs. Despite everyday concerns, the residents of Vetluga did not forget about their spiritual life.

Priests served in the Vetluga churches for a long time, and the Trinity Church was no exception. For many years, Vasily Zarnitsin, Father Nikolai Krylov, and Vyacheslav Ilyinsky served there. In 1935, the authorities imposed an unbearable tax on the church, which neither the priest nor the parishioners could pay, and the church was closed. Father Vyacheslav moved to the Catherine Church, where he served until his arrest in 1937. Initially, the closed church housed the city power station, and later the workshops of the Ulyanov plant branch, later known as AO "Termal."

The revival of the church began in 1993. In April, an Orthodox community was established, and in September 1995, a rector for the Trinity Church was appointed. Services began in the restored northern chapel of the church, although the main chapel still housed the foundry workshop of the plant. In 1996, the phased relocation of the plant to the main site was completed.