The original chambers, two stories high and with a deep basement under part of the building (structure No. 2), were smaller in size than the current building.

According to data from 1737, the first known owner of the buildings was chamberlain Polozov. The first graphic representation of the site development in full dates back to 1782.

Over the centuries, the ownership adapted to the tastes and needs of each new owner. As a result, the modern house 10, structure No. 2, became a multilayered monument with a rich construction history. The first floor includes the unchanged volume of the 17th-century chambers, vaulted rooms that appeared during the building's expansion in the 18th century, extensions to the northern facade from the mid-19th century, as well as a grand vestibule with a fireplace and staircase to the second floor from the early 20th century. The second floor combines the planning structure of the second half of the 18th and early 19th centuries (a suite of high grand rooms) with decorative finishes from the late 19th century (stucco cornices, tiled stoves, ornate cast-iron staircase railings). The building's facades are adorned with rich stucco decor from the 19th century.

In 2013, the building underwent restoration.

Due to the extremely unsatisfactory technical condition of the building, the priority task was to bring it out of emergency status. The roof was replaced, supporting structures and formwork were installed, the foundation and wooden beams of the ceilings were reinforced, injection work was carried out on the brick and white stone masonry of the walls and vaults, and the brickwork was restored. The load-bearing metal structures of the grand staircase were restored, dismantled, and recreated. Only after this was the restoration of the facades and interiors started, as well as the adaptation of the building for modern use.

The 19th-century facade decor was restored to its original form with the replacement of losses.

The restoration of historical interiors was carried out taking into account the architectural features of the construction periods of the 17th, 19th, and 20th centuries, with the exhibition of identified architectural details from the 17th century. The walls were cleared of later cladding and finishes, and the original color layer of the rooms was restored. Modern partitions were dismantled. Tiled stoves, the fireplace in the vestibule, and stucco decor (with the replacement of losses), the wrought iron railing, and the wooden handrail of the grand staircase were restored. The framed painting in the vestibule and stair hall, the carpentry fillings of window openings, dolomite steps, and landings of the grand staircase were recreated. Based on preserved fragments or analogs from the authentic era, parquet floors, door fillings of the first-floor rooms, grand rooms, and working offices on the second floor, as well as stoves made of unglazed tiles were restored.

In 2015, the chambers became a laureate of the Moscow Government's "Moscow Restoration" competition in the categories "For the Best Restoration Project" and "For the Best Organization of Repair and Restoration Work."