In the early 1880s, architect D. Chichagov built a beautiful blue mansion, adorned with ladies on the window sills, for Nikolai Alexandrovich Alexeev, the well-known mayor of Moscow. Special attention is drawn to the metal gates and fences. Nikolai Alexeev was a cousin of Stanislavsky, who would settle across the street 40 years later.

By the age of 30, Nikolai Alexandrovich headed the board of the Trading and Industrial Society "Vladimir Alexeev" and managed large enterprises in Pushkin, Kharkov, and the Moscow region. Since 1881, he was a member of the Moscow City Duma, and in November 1885, at the age of 33, he became the mayor of Moscow, gaining popularity due to his organizational talent. Before his arrival, the city's budget was in deficit and depended on the center, but thanks to Alexeev, Moscow received water supply and sewage systems. He personally funded the construction of two water towers at the Krestovskaya Zastava and initiated the relocation of slaughterhouses outside the city to Kalitniki. Under his leadership, the construction of the Historical Museum and the City Duma building was completed.

Nikolai Alexeev was a patron of several primary schools, and during his tenure, 30 city schools were built. In 1892, his relative P. Tretyakov donated his gallery to the city. Alexeev also initiated the creation of a well-known psychiatric hospital, with funds raised among Moscow philanthropists. However, in 1893, he was shot by a mentally ill person in his office. Dying, he bequeathed 300,000 rubles for the maintenance of the hospital, and the first two phases of the Alexeev Hospital opened after his death, in 1894 and 1896. Alexeev was buried in the Novospassky Monastery, but his grave was destroyed during the Soviet era.

After his death, the house was owned by his widow, Alexandra Vladimirovna, who was also involved in charity and served on the boards of schools and hospitals. The Alexeevs donated over two million rubles to charity. After her death, the mansion passed to Ivan Mindovsky, and then to Shamsi Asadullaev and his heirs.