The Abrikosov Mansion is located on the southwestern corner of the block where Ostozhenka Street and Turchaninov Lane intersect. The boundaries of this plot have changed over time.

In the mid-18th century, the area was bordered to the west by Ostozhenka, to the south by Stadychny Lane, and to the north by a dead end leading to the commoners' yards. There were five properties here: two small ones facing the street, two slightly larger, and the easternmost one was a vast courtyard. On this plot, owned by titular advisor I. T. Kolokoltsov, one stone building survived after the fire of 1752.

By 1762, the number of plots had decreased to four, and by 1764, to two. The northern boundary remained along the line of the dead end, which was partially absorbed by the yards. After the fire, the buildings were mostly restored with wooden structures.

By the early 1790s, there was one property covering more than 850 square fathoms, including the dead end and having an irregular shape. In 1796-1797, the buildings owned by Count P. A. Efimov were predominantly wooden. The only stone building remained at the site of the former "palatka."

From 1798 to 1809, the estate belonged to Prince P. N. Obolensky, the father of Decembrist E. P. Obolensky. During this period, the buildings were updated: in 1800, a part was added to the wooden main house, and by 1806, a two-story stone building was constructed. The old stone building was demolished, and new stables and a carriage house were built in its place.

In 1809, the property passed to the Bezobrazov nobles and remained with them until 1830. After the fire of 1812, the buildings were burned down, and until 1816, the plot was listed as empty. In 1817, wooden houses were built along the lane, and in 1822, the size of the manor house was increased.

In 1830, the estate was purchased by N. O. Skosyreva, during whose ownership the boundaries of the plot changed. In 1849, the eastern part was sold to A. I. Vinogradov, forming a new property.

The western part with the main house passed to E. I. Kudryavtseva in 1850. She redesigned the plot, building a new wooden house and two stone buildings. In the mid-1850s, two wooden structures were added to the house.

In the early 1870s, when the estate belonged to M. I. Ganeshina, the main house was wooden with a stone basement. In 1873, repairs were made, the facade was updated, and a porch was added. In 1875, a stone guardhouse appeared.

Until 1914, the buildings remained almost unchanged. In 1913, the property was purchased by M. F. Abrikosova. In 1914, she received permission to repair and remodel the terrace. In 1915-1916, internal repairs were conducted, and the courtyard buildings were reconstructed.

In 1926-1927, the house housed a Pedagogical Museum. The mansion was restored in the 2000s and currently serves as the reception for the Foreign Intelligence Service of Russia.