The Nikolo-Perervinsky monastery is located on a hill by the banks of the Moscow River. It was popular among the hierarchs of the Russian Church, such as Patriarch Adrian, Metropolitan Platon (Levshin) of Moscow, Metropolitan Filaret (Drozdov), Holy Martyr Vladimir (Bogoyavlensky), and others.

The architectural ensemble of the monastery includes churches: the Iver Cathedral, the Church of the Tolga Icon of the Mother of God, the temple of St. Sergius of Radonezh, and the Nikolsky and Assumption churches.

The first documentary mentions of the monastery date back to 1623. During the Time of Troubles, it was devastated by the Poles, but was restored under Tsar Feodor Mikhailovich.

In 1669, a second copy of the Iver Icon of the Mother of God, brought from Mount Athos, was established here, which became one of the most venerated relics.

In 1884, religious and moral readings began to be held at the monastery, and on October 31, 1906, a shelter for the deaf-mute was opened.

In 1924, the refectory was transferred for use as a club and dining room for the Children's Home of the Moscow Kursk Railway Administration. In July 1929, the Iver Chapel was demolished. In 1940, two churches were converted into a club and a pioneer house. After 1948, the building of the Nikolsky Cathedral housed production workshops of the Metal Stamping Plant, and until 1969, the factory for children's plastic toys. In 1969, the building was transferred to the ENIMS plant. The building of the Patriarchal cells was used as housing from the 1930s to the 70s, while the Church of the Tolga Icon of the Mother of God was used from the 1930s until 1966. In the 1950s, a factory building was added to the altar.

On January 8, 1991, the Nikolsky Cathedral was transferred to the community of the Russian Orthodox Church for indefinite free use.

All buildings of the monastery, except for the Nikolsky Cathedral, originally belonged to a branch of the rental enterprise 'Stankokonstruktsiya'. In 1993, by a decree of the Moscow Government, the entire monastery was transferred to the community of the Nikolsky Cathedral of the Russian Orthodox Church for indefinite free use.

Today, the monastery has a Sunday school and the Perervinsky Orthodox Spiritual Seminary, founded in 1775 by Metropolitan Platon (Levshin).