The State Museum of Artistic Culture of the Novgorod Land, located in Veliky Novgorod, is an important institution of culture and art. It is situated on the territory of the Desyatinnye Monastery, which is an architectural monument of the 14th and 19th centuries. Until 1994, creative workshops were housed in the northern wing of the monastery, where icon painters, woodcarvers, painters, and ceramic masters worked. In January 1994, the Regional Educational and Production Center for Artistic Creativity was established here, which received the status of the State Museum of Artistic Culture of the Novgorod Land in 2002.

The initiator of the museum's creation and its first director was Galina Viktorovna Gavrilova, a distinguished cultural worker of the Russian Federation. Among her like-minded colleagues were Inessa Leonidovna Zarakovskaya and Alexander Alekseevich Varentsov, who actively supported the artistic creativity of the Novgorod land.

The Center for Artistic Creativity was opened to visitors on April 12, 1994. The main goal of its establishment was to unite professional creative forces and promote the art of the Novgorod land. From the very beginning of the Center's work, preparations were underway to create the museum: subject and documentary materials were collected, and the future museum's fund was formed. The first works of art were donated to the Center on April 8, 1994, which became a tradition during exhibitions. The first exhibition, opened on April 12, 1994, showcased works by 27 professional Novgorod artists.

During the existence of the Center, about 200 exhibitions were organized, displaying works by artists from Veliky Novgorod, the region, other cities in Russia, and abroad. Thanks to cooperation with artists, the future museum's collections were constantly replenished. From 1994 to 2002, a collection of art by Novgorod artists from the second half of the 20th century was formed, totaling 2000 items.

In April 2002, the Center received the status of the State Museum of Artistic Culture of the Novgorod Land. Its collections hold over 6500 items, including sculpture, graphics, painting, glass, porcelain, medal art, and personal archives of artists.

In 2007, the museum became a collective member of the Petersburg Academy of Sciences and Arts. In 2011, a new exhibition "Museum Workshop of Porcelain" opened at the museum, and in 2012, "Cultural Heritage of Novgorod Monasteries". In 2016, an art space "Territory of Equals" was created.