The Exaltation of the Cross Men's Monastery is managed by the Eastern American Diocese of the Russian Orthodox Church Outside Russia. It is located in the foothills of the Appalachians in Wayne, West Virginia, surrounded by mountains and forests, which helps the inhabitants focus on prayer.

The community was founded in 1986 by Hieromonk Callistus (+1992) in House Springs, Missouri, where it existed for 14 years. By 1999, the number of brethren had doubled, and there were no free cells left. Then the monastery was offered a new plot of land and moved to West Virginia, completing the relocation in 2000.

Currently, about twenty monks, novices, and workers live at the Exaltation of the Cross Monastery. The main focus is on prayer, and the day for the inhabitants begins with Midnight Office at 5 a.m.

The spiritual center of the monastery is the temple. In 2000, the first small church was built, which now cannot accommodate all the believers. Plans are in place to construct a new, more spacious temple.

Every day, the monks perform a service for the great martyr and healer Panteleimon, praying for the sick and suffering.

Throughout the day, everyone works for the glory of God and to support the monastery. The obediences are diverse: a third of the monks work in workshops, where they produce incense according to the ancient tradition of Mount Athos, candles, soap, and other products. Some work on the monastery farms, providing the dining room with goat and cow milk, eggs, vegetables, honey, coffee, and other products that are sold in the church shop. The proceeds are important for the monastery's existence.

The inhabitants also participate in construction work, cooking, clerical work, and other obediences necessary for the life of the monastery.

In 2000, when the brethren settled in the new location, the infrastructure was virtually non-existent. Now, work is underway on projects that are to become the foundation for the future: updating roads, water supply, electrical systems, gas pipelines, building garages and storage for tools and building materials, as well as planting trees.