The museum, opened in 2011 in Wingen, was established on the site where René founded his factory in 1921. The architectural firm of Jean-Michel Wilmotte designed the museum. Its exhibition features items from the collections of Lalique's granddaughter Marie-Claude and the current owner of the enterprise, Swiss businessman Silvio Denz.

René Lalique was an outstanding jeweler and glass artist who left a significant mark in history. His name stands alongside renowned masters such as K. Fabergé, F. Boucheron, L.-F. Cartier, and L. Tiffany. Sarah Bernhardt wore jewelry created by Lalique, captivating the public. Among his clients was Russian Empress Alexandra Fyodorovna and other members of the aristocracy. Princess Tenisheva studied under Lalique.

The museum's exhibition includes sections dedicated to jewelry art, perfumery, exhibitions, as well as residential and public interiors. It recreates the interiors of the train "Côte d'Azur, Pullman Express" and features numerous photographs.

The museum also shows films about René Lalique's creative journey and the modern production process. Visitors can see how a product goes through all stages of creation, from sketch to logo application. Each item undergoes a long journey from molten mass to finished work of art.

Princess Tenisheva, passionate about enamel, revived this art that had faded in the 18th century. She spent much time in her workshop in Talashkino, working at the furnaces and galvanic baths. In photographs, she is captured in dark clothing, with rolled-up sleeves and an apron, focused on her work.

The maid would say to her: "What kind of lady are you? A real lady is dressed up, but you have all sorts of rubbish in your closets." Unsatisfied with the results, Maria sewed a "good" dress and went to study with René Lalique. She achieved such success that the master acknowledged there was nothing more to teach her. Upon returning to Talashkino, Tenisheva created over two hundred new shades of enamels. Her works were exhibited in London, Prague, Brussels, and Paris. In Italy, she became an honorary member of the Roman Archaeological Society. European experts recognized her as one of the best enamel masters. In her homeland, she defended a dissertation titled "Enamel and Inlay" and received an offer to take a chair in the history of enameling at the Moscow Archaeological Institute.