The neoclassical mansion at Vozdvizhenka, 14 was built between 1886 and 1888 by architect R.I. Klein for Varvara Alexeyevna Morozova, a well-known Moscow entrepreneur and philanthropist, owner of the Tver manufactory and a representative of prominent merchant families.

After her husband's death in 1885, Varvara Alexeyevna inherited his property and acquired the Dolgorukovs' estate on Vozdvizhenka, where she built the mansion in neoclassical style. This was one of Klein's first independent works, who would later create the Pushkin State Museum of Fine Arts. In the book by L.M. Smirnova and A.A. Demskaya, it is noted that Morozova's mansion resembles an Italian palazzo with a fountain in the garden and grand gates. The building's decor, although schematic, emphasizes the owner's status.

The interiors of the house, as noted by N.A. Varentsov, were designed in the English style, without excessive luxury. The construction of the mansion marked the beginning of a long collaboration between Morozova and Klein, who later designed charitable institutions for her.

The house on Vozdvizhenka became a center of cultural life in Moscow. Notable figures such as A.P. Chekhov, L.N. Tolstoy, A. Bely, and others visited. The actress M.G. Savina, who held charitable performances, stayed in the house. Varvara Morozova was an influential figure among the Moscow intelligentsia, and her home was under police surveillance. The opposition 'Union of Liberation' gathered there, and in 1905, Bolsheviks met here.

During the Soviet era, the mansion underwent re-planning, but the grand halls retained their original interiors. Restoration work was carried out in 2007 and 2013, restoring the facades and interiors. Today, the halls are used for receptions of foreign delegations. In 2013, the estate received an award for the best restoration project in the 'Moscow Restoration' competition.