The property at Gogolevsky Boulevard, 5/2, was part of the city estate of Prince Pyotr Vasilyevich Lopukhin in the 18th century, who held important state positions, including heading the Cabinet of Ministers under Paul I. His successful career was largely connected to his daughter Anna Gagarina, the favorite of the emperor.

The modern building, richly decorated, was constructed between 1850 and 1853 by architect Nikolai Ilyich Kozlovsky for State Councilor Pyotr Fedorovich Sekretarev. He was the son of the former chamberlain Grigory Potemkin and Catherine II, as well as a well-known patron who maintained a small theater in Lower Kislovsky Lane, known as 'Sekretarevka.'

The facade of the house is adorned with carved white stone columns and represents an example of the romantic style, echoing the Renaissance. This house is associated with the activities of architect Konstantin Andreyevich Ton, who lived here during the construction of the Cathedral of Christ the Savior in the 1850s. Experts believe that he created the design for Sekretarev, as the building's details resemble the Armory and the Grand Kremlin Palace.

From 1926 to 1934, the innovative educator Stanislav Teofilovich Shatsky lived and worked here.

There is a rumor that Vasily Stalin, the son of Joseph Stalin, lived in this house, but in reality, he resided in the neighboring mansion at Gogolevsky Boulevard, 7, which is located in the same courtyard as the Sekretarev estate.

In the second half of the 20th century, the building housed a dormitory for a textile factory from Butikovsky Lane.

In the 1990s, the building was renovated using original drawings. The work was carried out by the Moscow company 'ASK Novy Vek,' and the project was developed by the architectural bureau 'Triart-2000.'

In 2001, the organizations involved in the restoration were recognized in a competition for the best restoration and reconstruction of historical environment objects in Moscow, completed in 2000.

Today, the former estate houses offices of major Russian companies.