The urban estate at the beginning of Bolshaya Polyanka was built in the mid-18th century and belonged to the Kaluga merchant Mitrofan Petrovich Perepletchikov. He erected a two-story stone house, set back from the red line. In the late 18th century, the building was partially remodeled, adding new decorations to the facade. From 1800 to 1828, the estate was owned by Cleopatra Petrovna Nashchokina, the mother of Pavel Voinovich Nashchokina, who was a close friend of Alexander Sergeyevich Pushkin. Correspondence and memoirs of contemporaries confirm their strong friendship, which lasted until Pushkin's death in 1837. Pavel Voinovich was born and spent his childhood in this house. He was baptized in the Church of Cosmas and Damian in Kadashi, which has not survived to this day.

Nashchokin left his family home at the age of thirteen but returned to visit his mother and sister, who became the owner of the estate in 1828. It is possible that Pushkin also visited here, as he was acquainted with the Nashchokin family. The estate was not damaged in the fire of 1812, and its composition was preserved until the mid-19th century. At that time, the new owner, Moscow merchant Sergey Sergeyevich Egorov, made the house profitable. It was adapted for apartments, adding porches and halls, but the layout of the 18th century was preserved.

After the end of the Soviet period, the interiors from the late 19th and early 20th centuries, such as stucco, rosettes, oak parquet, and doors, were lost. In the 1990s, during restoration, the original 18th-century decorations, characteristic of the transition from Baroque to Classicism, were uncovered on the side facade. The main facade of the house, facing Bolshaya Polyanka, is typical of Moscow classicism with a central risalit and triangular pediment.

In 1999, in honor of the 200th anniversary of Pushkin's birth, the Nashchokin mansion was granted the status of a cultural heritage site of regional significance. Currently, the house is rented by one of the Moscow companies, but it is vacant and almost unused.