In the first quarter of the 19th century, the former serfs of Count Sheremetev, the Nabilkov brothers, acquired an extensive estate on the even side of the modern Mira Avenue. The building located at: Mira Avenue, 50, was constructed by architect Yelizvoy Semyonovich Nazarov for the Lobkov family in 1816-17. In 1827, Fyodor Fyodorovich Nabilkov became its owner.

Brothers Vasily and Fyodor Nabilkov gained fame in Russia due to their unusual fate and generous philanthropy. Hailing from the Yaroslavl province, they were serfs classified as "obrok peasants," obligated to regularly pay their master certain amounts earned through crafts or trade.

After Fyodor Fyodorovich married a bride with a good dowry in the early 1790s, the brothers moved to the capitals. Vasily Fyodorovich engaged in textile trade in St. Petersburg, while Fyodor Fyodorovich settled in Moscow. His trade in fabrics, from "landlord" to "arshin" goods, amassed significant wealth. With his funds, the bell tower and stone buildings in the Alexander Nevsky Lavra were constructed, as well as a hermitage on Valaam, the Nikolayevskaya Berlyukovskaya desert, and work was carried out on Athos. Childless and deeply religious, the Nabilkov brothers donated their capital to charity.

From 1828 to 1831, a "poorhouse for the elderly" was located in Fyodor Fyodorovich's estate on Mira Avenue, and in 1831-32 the building was converted into a school. The secondary educational institution, founded with the brothers' funds, had a high reputation in Moscow. It taught painting, engraving, and printing technology. Among its graduates were architect V.K. Oltarzhevsky, actor and writer I.F. Gorbunov, and local historian A.F. Rodin.

The facade of the building is adorned with a balcony supported by two pilasters and six columns resting on an arcade. The main entrance leads through an external gallery. On both sides of the colonnade are symmetrical risalits with arched niches and slender columns topped with pediments. In the late 1980s, the building was reinforced with metal structures, and in 2015, the facade was renovated.

Over the past 25 years, the building has housed various institutions, including clinics, a multifunctional center, a dental clinic, a mathematics club, and an institute of positive psychotherapy.