The multi-apartment income house, located at the corner of Chisty Lane, formerly known as Obukhov, and the right side of Prechistenka, was built in 1904 according to the design of architect Semyon Fyodorovich Kulagin. This massive four-story yellow building stands out with its white rustication on the first floor. Several windows on the facade facing Prechistenka are adorned with porticos featuring half-columns. The facade facing Chisty Lane has two large windows that connect the second and third floors.

In the early 20th century, the uncle of Mikhail Afanasyevich Bulgakov, Nikolai Mikhailovich Pokrovsky, a well-known gynecologist, lived here. His other uncle, therapist Mikhail Mikhailovich Pokrovsky, often visited and stayed in a specially designated room. Mikhail Afanasyevich frequently visited apartment No. 12 at his uncles' place both before and after moving to Moscow.

In the second entrance of the former "Kalabukhovsky House," on the bel étage, was the apartment of Philip Philipovich Preobrazhensky from the novella "Heart of a Dog," whose prototype was N.M. Pokrovsky. In the operating room of his large professor's apartment, Preobrazhensky conducted a bold experiment on rejuvenation with a pituitary gland transplant, which led to the unexpected "complete humanization" of the dog Sharik. Here, the newly minted citizen Sharikov claimed his rightful "16 square arshins" of the professor's apartment.

After the publication of "Heart of a Dog," the novella became a source of many quotes, one of which, "the Kalabukhovsky House is gone," is related to house No. 1 on Chisty Lane:

"Zinushka, what does this mean? They held another general meeting, Philip Philipovich, said Zina. Again!, Philip Philipovich exclaimed mournfully. Well, now, it seems, the Kalabukhovsky House is gone. We'll have to leave, but where to, one might ask? Everything will go smoothly. At first, singing every evening, then the pipes in the toilets will freeze, then the boiler in the steam heating will burst, and so on. The lid to Kalabukhov!"

In this same house, Soviet physicist and founder of dynamic physics of high pressures Lev Vladimirovich Altshuler was born. In his memoirs, he wrote: "In 1910, my grandfather, a pharmacist, rented an apartment on the fourth floor of house 24 from the landlord Kulagin for his son, located at the corner of Prechistenka Street and Obukhov Lane, next to the fire station. We lived in the third entrance, while Bulgakov's uncle, who became the prototype for Professor Preobrazhensky, lived in the second. I was born in November 1913 in this house."