On May 18, 1949, Father Ioann Klyarovich acquired plot 5717 on California Street with a small house built in 1907. A year later, he transferred this property to a corporation, registering it as "San Francisco Church Parish in Honor of the Kazan Icon of the Mother of God." The first clergyman was Father Ioann Klyarovich, with the church warden Arseniy Gram, and parish council members Max Kern, Vasily Chetyrkin, Nikolai Neklyudov, and Vladimir Norton.

In 1950, permission was obtained to increase the capacity to 50 people. With funds raised by parishioners, the house was converted into a small church. In December 1961, the house at 5725-5727 California Street, next to the church, was purchased. While construction was underway, services were held on the lower floor. The parish grew thanks to immigrants from Europe and the Far East. In 1963, the question arose about purchasing a new plot or renovating the church at the old site. It was decided to stay and expand the church.

In 1967, the city granted permission to build a new temple, estimated to cost $60,000. In 1968, architect Vladislav Sergeyevich Danilov and engineer Vladimir Vladimirovich Granitov took on the project for free. Vladimir Vladimirovich also completed all the interior woodwork. In May 1968, the dome was ceremoniously transported across the bridge and installed in place. A bell found outside the city was installed under the guidance of Boris Nikolaevich Borzov. Wells Fargo Bank provided a loan of $25,000, which was repaid over five years with the help of parishioners and donors. The exterior of the church was completed.

The interior frescoes were done by the late Father Kyprian from the Jordanville Monastery. The walls were prepped for free by V. Shibinsky. He painted the icon of the Kazan Mother of God and repaired the large cross built by Father Ioann Klyarovich in memory of the royal family. Every year, on July 17, a service is held in the church in their honor. The icon and cross have become historical treasures of the Kazan parish.

The first iconostasis was transported and donated to the church in Russian River, and the crucifix was moved to the church in Calistoga. A new crucifix was created by Vladimir V. Krasovsky. The Kazan church is considered the most beautiful in San Francisco. Veterans of World War I, the revolution, and cadets have adopted the Kazan church as their parish.

The rectors of the Kazan church over 60 years have included: Father Ioann Klyarovich, Father Pavel Sakhnovsky, Protopresbyter Nikolai Kolchev, Protopresbyter Vladimir Glindsky, Protopresbyter Alexey Poluektov, and Hieromonk Juvenaly Kherin. Father Gleb Gulyaev served as deacon for a long time.

A significant contribution to the church's development was made by warden Andrey Andreevich Abramov, his sisters, and his wife Irina Antonovna, as well as the sisterhood. The sisterhood continues its work, organizing lunches for parishioners every Sunday, which fosters their communication.

The choirmasters have included Mr. Grabovsky, Serafim N. Kolchev, Viktor V. Nekhonov, Georgiy A. Perekrestov, T. Yarosheva, and N. Masenko.