The stone two-altar church with the main altar dedicated to the Tikhvin Icon of the Mother of God was reportedly built in the late 17th century, or according to other sources, in 1749. In the mid-19th century, the church underwent reconstruction. In 1864, it was damaged by fire but was soon restored. By 1882, the church occupied an area of 320 square fathoms and had a three-tiered bell tower. In the summer of 1930, the bells were removed, and by 1936, the church was completely dismantled.

The architectural and urban planning significance of the Tikhvin Church lay in shaping the vertical silhouette of the southern slope of the Volga hill. It was located at the corner of the intersection of Tikhvinskaya Street, now Plekhanova, and the modern S. Khalturina Lane. Having existed for almost two centuries, the Tikhvin Church was a stone structure built in 1749. After the fire in 1864, the church was restored.

In the 1930s, the Tikhvin Church was demolished, and in 1987-1988, a two-story hotel "Oktyabrskaya" was built on this site.

Situated on one of the terraces of the Volga hill, the church had significant architectural and urban planning importance for the silhouette of this part of the city. It was equidistant from the Nikolayevsky Cathedral as the Vladimir Church, creating a balanced composition in the urban panorama.

The church included a three-tiered bell tower with a light frame tower and an onion dome topped with a cross. Next was the refectory with a vaulted ceiling and a gable roof. To the east of the refectory was a two-light octagonal church, topped with a dome featuring a blind lantern and a small onion dome crowned with an eight-pointed gilded cross. The entrance to the church was from the south through a narthex in the bell tower.

The dimensions of the church in plan were modest: the length was about 23 meters, and the width was 17 meters. The architectural significance also included the fence with gates in the form of an arch with a dome on a blind drum, located above the middle part of the arch, representing notable small architectural forms.