Originally, the church was named Episcopal Church Harold’s Cross and was built in 1838 by architects John Louche and R. and W. Togue. In 1914, a southwest bell tower was added, which was dismantled in the last 15 years for safety reasons. The first priest in 1838 was Robert James McGee, and a house for the parish priest was built at the intersection of Harold’s Cross Road and Leinster Road West between 1875 and 1880. The granite building, resembling a castle, may mislead regarding the interior decoration of the church. Inside, there is a ribbed blue ceiling supported by slender columns, and the rear gallery is adorned with a melodic organ. The church has many beautiful stained glass windows, among which one of the most beautiful windows from 1960 was created by the famous Irish glass artist Catherine A. O’Brien from the An Tur Gloine studio. Her work, titled 'The Good Samaritan,' reflects the charity of the Harold’s Cross area in support of The Poor Clares shelter. On the first floor and gallery, one can still see fireplaces that likely caused quite a bit of trouble for the church officials in the absence of central heating.

The church was closely associated with the Boy Scouts movement, and a collection of posters and flags has been preserved. In the past, soldiers from the Portobello barracks (now Cathal Brugha) marched down Harold’s Cross Road to the church for special services. The large basement was used as a primary school and sometimes for bowling and billiards, but it had to be closed in the 70s due to flooding from the Poddle River, which flows behind the church. Hurricane Clare in 1986 also caused significant flooding. The laundry and mill near Harold’s Cross helped manage the river's flow.

Among the parishioners was Mr. Coulter, who worked as a gravedigger at the cemetery behind the church. The church organized community events and trips on double-decker buses, where Mr. Coulter's accordion entertained the passengers. On summer evenings, his music delighted the neighbors. In 1903, the Anglican church of Harold’s Cross received parish status, and in 1977 it became part of the Rathmines parish. Later, due to the decline of the Protestant community, the church was closed on June 27, 2001, after a thanksgiving service conducted by the Archbishop of Ireland, Dr. Walton Empey.

In November 2001, a parish of the Russian Orthodox Church was opened at Harold’s Cross following a visit by Metropolitan Kirill to Ireland. The consecration took place in February 2003. Services are held regularly: on Saturdays, liturgy in the attached parishes (Cork, Waterford, Galway), all-night vigils, Sunday Divine Liturgy in Church Slavonic and English, as well as on major feasts, days of remembrance of saints, and memorial services for the deceased. Approximately 150-200 people receive communion weekly, and up to 1000 during holidays (Easter, Christmas). Since the parish's establishment, there have been baptisms (300), weddings (30), and funerals (15). The parish is multinational: Russians, Ukrainians, Moldovans, Georgians, Serbs, Irish, and French. About 20 immigrants from Western countries have converted to Orthodoxy.

An educational school operates at the church, supporting the Russian language and culture in Russian-speaking families, with around 70 students. All teachers are professional educators with extensive experience. There is also a church school, library, and church shop, which offers about 300 titles of books in two languages. A weekly bulletin is published, the website is updated, pastoral conversations and gospel readings are conducted in Russian and English. A monthly 'Orthodoxy' page appears in a Russian-language newspaper.